| Gene Information | |
|---|---|
| Gene Name | LOXL4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 756 |
| Protein Names | Lysyl oxidase homolog 4 (EC 1.4.3.-) (Lysyl oxidase-like protein 4) (Lysyl oxidase-related protein C) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000138131 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q96JB6 |
| Gene Card | LOXL4 |
| Uniprot ID | Q96JB6 |
| Pfam | PF01186; PF00530 |
| In ASD | no |
| Allosteric Prediction | no (-0.830184752) |
| Ortholog in Animals | Alpaca_ LOXL4 ( ortholog_one2one ) Dog_ LOXL4 ( ortholog_one2one ) GuineaPig_ LOXL4 ( ortholog_one2one ) Macaque_ LOXL4 ( ortholog_one2one ) Mouse_ Loxl4 ( ortholog_one2one ) Pig_ LOXL4 ( ortholog_one2one ) Rat_ Loxl4 ( ortholog_one2one ) Rabbit_ LOXL4 ( ortholog_one2one ) |
| Ohnologs | LOXL3, LOXL2 |
| Paralogs | CD6, LOX, SSC4D, SSC5D, LGALS3BP, SCART1, CD163, PRSS12, DMBT1, LOXL3, CD5, LOXL1, CD5L, LOXL2, CD163L1 |
| Tissue | bone.marrow, cervix, pancreas, parotid.gland, penis, submandibular.gland, testis, uterus |
| Tissue Specificity | Expressed in many tissues, the highest levels among the tissues studied being in the skeletal muscle, testis and pancreas. Expressed in cartilage. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | NA |
| DBSNP | rs33995374 rs11189525 rs1983864 |
| Subcellular location [CC] | Secreted, extracellular space {ECO:0000305}. |
| Mouse PG classification | NA |
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