| Gene Information | |
|---|---|
| Gene Name | C16orf77 |
| Organism | Homo sapiens (Human) |
| Gene Length | 242 |
| Protein Names | Interleukin-34 (IL-34) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q6ZMJ4 |
| Gene Card | IL34 |
| Uniprot ID | Q6ZMJ4 |
| Pfam | PF15036 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Detected in the sinusoidal epithelium in the red pulp of spleen (at protein level). Predominantly expressed in spleen. Also detected in a range of other tissues including heart, brain, lung, liver, kidney, thymus, testis, ovary, small intestine, prostate and colon. {ECO:0000269|PubMed:18467591}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.010990(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4DKC (X-ray 1.85A ) 4DKD (X-ray 3.00A ) 4DKE (X-ray 3.00A ) 4DKF (X-ray 2.61A ) |
| DBSNP | rs8046424 rs7206509 |
| Subcellular location [CC] | Secreted {ECO:0000269|PubMed:18467591}. |
| Mouse PG classification | NA |
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