| Gene Information | |
|---|---|
| Gene Name | C16orf47 |
| Organism | Homo sapiens (Human) |
| Gene Length | 3703 |
| Protein Names | Zinc finger homeobox protein 3 (AT motif-binding factor 1) (AT-binding transcription factor 1) (Alpha-fetoprotein enhancer-binding protein) (Zinc finger homeodomain protein 3) (ZFH-3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | NA |
| Gene Card | ZFHX3 |
| Uniprot ID | Q15911 |
| Pfam | PF00046; PF00096 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Not found in normal gastric mucosa but found in gastric carcinoma cells (at protein level). Expression is higher in ER-positive breast tumors than ER-negative breast tumors (at protein level). {ECO:0000269|PubMed:17330845, ECO:0000269|PubMed:20599712, ECO:0000269|PubMed:20720010, ECO:0000269|PubMed:22452784}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2DA1 (NMR - ) 2DA2 (NMR - ) 2DA3 (NMR - ) |
| DBSNP | rs7193297 rs58480263 rs16971436 rs2073852 rs4788682 rs2213978 rs8044440 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:20599712, ECO:0000269|PubMed:24651376}. Cytoplasm {ECO:0000269|PubMed:20599712}. Note=Translocates from the cytoplasm to the nucleus following TGF-beta stimulation. Expressed in nuclear body (NB)-like dots in the nucleus some of which overlap or closely associate with PML body. {ECO:0000269|PubMed:20599712, ECO:0000269|PubMed:24651376}. |
| Mouse PG classification | NA |
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