| Gene Information | |
|---|---|
| Gene Name | RABGEF1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 491 |
| Protein Names | Rab5 GDP/GTP exchange factor (RAP1) (Rabaptin-5-associated exchange factor for Rab5) (Rabex-5) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 886 ( ENSG00000154710 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9UJ41 |
| Gene Card | RABGEF1 |
| Uniprot ID | Q9UJ41 |
| Pfam | PF18151; PF02204; PF01754 |
| In ASD | yes |
| Allosteric Prediction | no (-0.471773152) |
| Ortholog in Animals | Alpaca_ RABGEF1 ( ortholog_one2one ) Dog_ RABGEF1 ( ortholog_one2one ) GuineaPig_ RABGEF1 ( ortholog_one2one ) Macaque_ RABGEF1 ( ortholog_one2one ) Mouse_ Rabgef1 ( ortholog_one2one ) Pig_ RABGEF1 ( ortholog_one2one ) Rat_ Rabgef1 ( ortholog_one2one ) Rabbit_ RABGEF1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | RINL, RIN2, RIN3, RIN1, VPS9D1, GAPVD1 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1TXU (X-ray 2.35A ) 2C7M (X-ray 2.40A ) 2C7N (X-ray 2.10A ) 2OT3 (X-ray 2.10A ) 4N3X (X-ray 2.00A ) 4N3Y (X-ray 2.20A ) 4N3Z (X-ray 3.10A ) 4Q9U (X-ray 4.62A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:12505986}. Early endosome {ECO:0000269|PubMed:12505986}. Recycling endosome {ECO:0000269|PubMed:12505986}. |
| Mouse PG classification | NA |
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