| Gene Information | |
|---|---|
| Gene Name | C14orf66 |
| Organism | Homo sapiens (Human) |
| Gene Length | 323 |
| Protein Names | Sphingolipid delta(4)-desaturase/C4-monooxygenase DES2 (EC 1.14.18.5) (EC 1.14.19.17) (Degenerative spermatocyte homolog 2) (Sphingolipid 4-desaturase) (Sphingolipid C4-monooxygenase) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q6QHC5 |
| Gene Card | DEGS2 |
| Uniprot ID | Q6QHC5 |
| Pfam | PF00487; PF08557 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Highly expressed in skin, intestine and kidney. {ECO:0000269|PubMed:15063729}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs7157599 rs4905937 |
| Subcellular location [CC] | Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q8R2F2}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q8R2F2}. |
| Mouse PG classification | NA |
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