| Gene Information | |
|---|---|
| Gene Name | C10orf90 |
| Organism | Homo sapiens (Human) |
| Gene Length | 699 |
| Protein Names | (E2-independent) E3 ubiquitin-conjugating enzyme FATS (EC 2.3.2.-) (Centrosomal protein C10orf90) (E2/E3 hybrid ubiquitin-protein ligase FATS) (Fragile-site associated tumor suppressor homolog) (FATS) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000154493 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q96M02 |
| Gene Card | C10orf90 |
| Uniprot ID | Q96M02 |
| Pfam | PF15309; PF17730 |
| In ASD | no |
| Allosteric Prediction | no (-0.931776341) |
| Ortholog in Animals | Alpaca_ C10H10orf90 ( ortholog_one2one ) Dog_ C10orf90 ( ortholog_one2one ) GuineaPig_ C10orf90 ( ortholog_one2one ) Macaque_ C9H10orf90 ( ortholog_one2one ) Mouse_ D7Ertd443e ( ortholog_one2one ) Pig_ C10orf90 ( ortholog_one2one ) Rat_ D7Ertd443e ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | ALMS1, CEP295, CEP295NL |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs11558415 rs11245008 rs11245007 rs12412320 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:20844083}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:20844083}. Note=Localizes to the actin cytoskeleton in a proportion of cells. Colocalizes with centriolar acetylated tubulin. {ECO:0000269|PubMed:20844083}. |
| Mouse PG classification | NA |
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