Gene Information | |
---|---|
Gene Name | BTLA |
Organism | Homo sapiens (Human) |
Gene Length | 289 |
Protein Names | B- and T-lymphocyte attenuator (B- and T-lymphocyte-associated protein) (CD antigen CD272) |
Target Name | b- and t-lymphocyte attenuator |
Target Type | Clinical trial target |
Gene Age | 544 ( ENSG00000186265 ) |
Evolutionary Stage | Mammalia |
AlphaFoldDB | Q7Z6A9 |
Gene Card | BTLA |
Uniprot ID | Q7Z6A9 |
Pfam | PF00047 |
In ASD | no |
Allosteric Prediction | no (-0.697514723) |
Ortholog in Animals | Alpaca_ BTLA ( ortholog_one2one ) Dog_ BTLA ( ortholog_one2one ) GuineaPig_ BTLA ( ortholog_one2one ) Macaque_ BTLA ( ortholog_one2one ) Mouse_ Btla ( ortholog_one2one ) Rat_ Btla ( ortholog_one2one ) |
Ohnologs | NA |
Paralogs | NA |
Tissue | appendix, lymph.node, spleen, tonsil |
Tissue Specificity | NA |
Pharmacological Animal Models | NA |
Gene Ontology (biological process) |
|
Gene Ontology (cellular component) |
|
Gene Ontology (molecular function) |
|
PDB | 2AW2 (X-ray 2.80A ) 6NYP (X-ray 2.70A ) |
DBSNP | rs16859633 rs2931761 rs9288952 |
Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:12796776}; Single-pass type I membrane protein {ECO:0000305}. |
Mouse PG classification | NA |
click here to return to the previous page |