| Gene Information | |
|---|---|
| Gene Name | BTLA |
| Organism | Homo sapiens (Human) |
| Gene Length | 289 |
| Protein Names | B- and T-lymphocyte attenuator (B- and T-lymphocyte-associated protein) (CD antigen CD272) |
| Target Name | b- and t-lymphocyte attenuator |
| Target Type | Clinical trial target |
| Gene Age | 544 ( ENSG00000186265 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | Q7Z6A9 |
| Gene Card | BTLA |
| Uniprot ID | Q7Z6A9 |
| Pfam | PF00047 |
| In ASD | no |
| Allosteric Prediction | no (-0.697514723) |
| Ortholog in Animals | Alpaca_ BTLA ( ortholog_one2one ) Dog_ BTLA ( ortholog_one2one ) GuineaPig_ BTLA ( ortholog_one2one ) Macaque_ BTLA ( ortholog_one2one ) Mouse_ Btla ( ortholog_one2one ) Rat_ Btla ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | appendix, lymph.node, spleen, tonsil |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2AW2 (X-ray 2.80A ) 6NYP (X-ray 2.70A ) |
| DBSNP | rs16859633 rs2931761 rs9288952 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:12796776}; Single-pass type I membrane protein {ECO:0000305}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |