Gene Information
Gene NameKAT8
OrganismHomo sapiens (Human)
Gene Length458
Protein NamesHistone acetyltransferase KAT8 (EC 2.3.1.48) (Lysine acetyltransferase 8) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 1) (MYST-1) (hMOF)
Target NameNA
Target TypeNA
Gene Age1292 ( ENSG00000103510 )
Evolutionary StageEukaryota
AlphaFoldDBQ9H7Z6
Gene CardKAT8
Uniprot IDQ9H7Z6
PfamPF01853; PF11717; PF17772
In ASDno
Allosteric Predictionno (-0.555915089)
Ortholog in AnimalsAlpaca_ KAT8 ( ortholog_one2one )
Dog_ KAT8 ( ortholog_one2one )
GuineaPig_ KAT8 ( ortholog_one2one )
Macaque_ KAT8 ( ortholog_one2one )
Mouse_ Kat8 ( ortholog_one2one )
Pig_ KAT8 ( ortholog_one2one )
Rat_ Kat8 ( ortholog_one2one )
Rabbit_ KAT8 ( ortholog_one2one )
OhnologsKAT7
ParalogsKAT6B, KAT6A, PHF10, KAT7, DPF1, DPF3, DPF2, RSF1, KAT5
TissueNA
Tissue SpecificityNA
Pharmacological Animal Models0.006520(Chimpanzee);0.013377(Mouse);0.001293(Rat);0.027027(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 2GIV  (X-ray  1.94A  )  2PQ8  (X-ray  1.45A  )  2Y0M  (X-ray  2.70A  )  3QAH  (X-ray  2.10A  )  3TOA  (X-ray  3.00A  )  3TOB  (X-ray  2.70A  )  4DNC  (X-ray  2.05A  )  5H43  (X-ray  2.30A  )  5J8C  (X-ray  2.17A  )  5J8F  (X-ray  2.60A  )  5WCI  (X-ray  1.78A  )  6BA2  (X-ray  1.85A  )  6BA4  (X-ray  1.95A  )  6CT2  (X-ray  2.13A  )  6OIN  (X-ray  1.70A  )  6OIO  (X-ray  1.70A  )  6OIP  (X-ray  1.80A  )  6OIQ  (X-ray  1.75A  )  6OIR  (X-ray  2.03A  )  6OWH  (X-ray  2.00A  )  6OWI  (X-ray  1.75A  )  6PD8  (X-ray  2.74A  )  6PD9  (X-ray  2.80A  )  6PDA  (X-ray  2.45A  )  6PDB  (X-ray  2.42A  )  6PDC  (X-ray  1.96A  )  6PDD  (X-ray  2.15A  )  6PDE  (X-ray  2.22A  )  6PDF  (X-ray  2.22A  )  6PDG  (X-ray  1.92A  )  7CMR  (X-ray  2.20A  ) 
DBSNP NA 
Subcellular location [CC]Nucleus {ECO:0000269|PubMed:10786633, ECO:0000269|PubMed:20018852, ECO:0000269|PubMed:31794431}. Chromosome {ECO:0000305|PubMed:10786633}.
Mouse PG classificationNA
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