| Gene Information | |
|---|---|
| Gene Name | BTF3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 584 |
| Protein Names | Butyrophilin subfamily 3 member A3 |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1292 ( ENSG00000145741 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | O00478 |
| Gene Card | BTN3A3 |
| Uniprot ID | O00478 |
| Pfam | PF13765; PF00622; PF07686 |
| In ASD | no |
| Allosteric Prediction | no (-0.851363915) |
| Ortholog in Animals | Dog_ BTF3 ( ortholog_one2one ) Mouse_ Btf3 ( ortholog_one2one ) Rat_ RGD1559667 ( ortholog_one2one ) |
| Ohnologs | BTF3L4 |
| Paralogs | TAB2, BTF3L4, TAB3 |
| Tissue | NA |
| Tissue Specificity | Detected in peripheral blood mononuclear cells and in T-cells (at protein level). Detected in spleen and lymphocytes. {ECO:0000269|PubMed:20610803}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4F8T (X-ray 2.38A ) 5ZZ3 (X-ray 3.00A ) 6J0G (X-ray 1.60A ) 6J0K (X-ray 2.00A ) 6J0L (X-ray 1.95A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:21918970, ECO:0000269|PubMed:22767497}; Single-pass type I membrane protein {ECO:0000269|PubMed:21918970, ECO:0000269|PubMed:22767497}. |
| Mouse PG classification | NA |
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