| Gene Information | |
|---|---|
| Gene Name | BSN |
| Organism | Homo sapiens (Human) |
| Gene Length | 3926 |
| Protein Names | Protein bassoon (Zinc finger protein 231) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000164061 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | NA |
| Gene Card | BSN |
| Uniprot ID | Q9UPA5 |
| Pfam | PF05715 |
| In ASD | no |
| Allosteric Prediction | no (-0.774620248) |
| Ortholog in Animals | Alpaca_ BSN ( ortholog_one2one ) Dog_ BSN ( ortholog_one2one ) GuineaPig_ BSN ( ortholog_one2one ) Macaque_ BSN ( ortholog_one2one ) Mouse_ Bsn ( ortholog_one2one ) Pig_ BSN ( ortholog_one2one ) Rat_ Bsn ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | PCLO |
| Tissue | brain, cerebral.cortex, cerebellar.hemisphere, cerebellum |
| Tissue Specificity | Exclusively expressed in brain. {ECO:0000269|PubMed:9806829}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs34762726 rs35762866 rs2005557 |
| Subcellular location [CC] | Cytoplasm {ECO:0000250|UniProtKB:O88778}. Presynaptic active zone {ECO:0000250|UniProtKB:O88778}. Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:O88778}. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane {ECO:0000250|UniProtKB:O88778}; Peripheral membrane protein {ECO:0000250|UniProtKB:O88778}. Note=In retina, is localized in the outer plexiform layer at ribbon synapses formed by rods and cones but was absent from basal synaptic contacts formed by cones. In the retinal inner plexiform layer localized to conventional inhibitory GABAergic synapses, made by amacrine cells, but absent from the bipolar cell ribbon synapses. {ECO:0000250|UniProtKB:O88778}. |
| Mouse PG classification | NA |
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