Gene Information
Gene NameBRWD3
OrganismHomo sapiens (Human)
Gene Length1802
Protein NamesBromodomain and WD repeat-containing protein 3
Target NameNA
Target TypeNA
Gene Age645 ( ENSG00000165288 )
Evolutionary StageEukaryota
AlphaFoldDBQ6RI45
Gene CardBRWD3
Uniprot IDQ6RI45
PfamPF00439; PF00400
In ASDno
Allosteric Predictionno (-0.977478179)
Ortholog in AnimalsAlpaca_ BRWD3 ( ortholog_one2one )
Dog_ BRWD3 ( ortholog_one2one )
GuineaPig_ BRWD3 ( ortholog_one2one )
Macaque_ BRWD3 ( ortholog_one2one )
Mouse_ Brwd3 ( ortholog_one2one )
Pig_ BRWD3 ( ortholog_one2one )
Rat_ Brwd3 ( ortholog_one2one )
Rabbit_ BRWD3 ( ortholog_one2one )
OhnologsPHIP, BRWD1
ParalogsBRWD1, PHIP
TissueNA
Tissue SpecificityFound in most adult tissues. Down-regulated in a majority of the B-CLL cases examined. {ECO:0000269|PubMed:15543602}.
Pharmacological Animal ModelsNULL(Chimpanzee);0.035650(Mouse);NULL(Rat);NULL(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs3122407  rs137853272 
Subcellular location [CC]NA
Mouse PG classificationHPG
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