| Gene Information | |
|---|---|
| Gene Name | BRR2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 2136 |
| Protein Names | U5 small nuclear ribonucleoprotein 200 kDa helicase (EC 3.6.4.13) (Activating signal cointegrator 1 complex subunit 3-like 1) (BRR2 homolog) (U5 snRNP-specific 200 kDa protein) (U5-200KD) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | O75643 |
| Gene Card | SNRNP200 |
| Uniprot ID | O75643 |
| Pfam | PF00270; PF00271; PF18149; PF02889 |
| In ASD | yes |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Widely expressed. {ECO:0000269|PubMed:19878916}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.197457(Rat);0.151752(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
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| PDB | 2Q0Z (X-ray 2.00A ) 3JCR (EM 7.00A ) 4F91 (X-ray 2.70A ) 4F92 (X-ray 2.66A ) 4F93 (X-ray 2.92A ) 4KIT (X-ray 3.60A ) 5O9Z (EM 4.50A ) 5URJ (X-ray 2.75A ) 5URK (X-ray 2.95A ) 5URM (X-ray 2.80A ) 5XJC (EM 3.60A ) 5YZG (EM 4.10A ) 5Z56 (EM 5.10A ) 5Z57 (EM 6.50A ) 5Z58 (EM 4.90A ) 6AH0 (EM 5.70A ) 6AHD (EM 3.80A ) 6FF7 (EM 4.50A ) 6ICZ (EM 3.00A ) 6QDV (EM 3.30A ) 6QW6 (EM 2.92A ) 6QX9 (EM 3.28A ) 6S8O (X-ray 3.17A ) 6S8Q (X-ray 2.39A ) 6S9I (X-ray 2.60A ) 7A5P (EM 5.00A ) 7ABG (EM 7.80A ) 7ABI (EM 8.00A ) 7BDI (X-ray 2.80A ) 7BDJ (X-ray 2.59A ) 7BDK (X-ray 2.52A ) 7BDL (X-ray 2.69A ) 7DVQ (EM 2.89A ) 7OS1 (EM 3.30A ) 7OS2 (EM 2.76A ) 7PX3 (EM 3.05A ) 7W5B (EM 4.30A ) |
| DBSNP | rs959069360 rs527236113 rs527236114 rs1457428682 rs397514575 rs267607077 rs397514574 rs749546665 rs201691299 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:28502770, ECO:0000269|PubMed:28781166, ECO:0000269|PubMed:29301961, ECO:0000269|PubMed:29360106, ECO:0000269|PubMed:29361316, ECO:0000269|PubMed:30315277, ECO:0000269|PubMed:30705154, ECO:0000269|PubMed:30728453, ECO:0000269|PubMed:9539711}. |
| Mouse PG classification | NA |
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