| Gene Information | |
|---|---|
| Gene Name | SIGLEC11 |
| Organism | Homo sapiens (Human) |
| Gene Length | 698 |
| Protein Names | Sialic acid-binding Ig-like lectin 11 (Sialic acid-binding lectin 11) (Siglec-11) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000161640 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q96RL6 |
| Gene Card | SIGLEC11 |
| Uniprot ID | Q96RL6 |
| Pfam | PF13895; PF07686 |
| In ASD | no |
| Allosteric Prediction | no (-1.377659146) |
| Ortholog in Animals | Alpaca_ SIGLEC11 ( ortholog_many2many ) Mouse_ Siglecg ( ortholog_one2many ) Rat_ Siglec10 ( ortholog_one2many ) |
| Ohnologs | NA |
| Paralogs | MAG, SIGLECL1, CD22, SIGLEC16, SIGLEC10, SIGLEC5, SIGLEC7, SIGLEC8, CD33, SIGLEC9, SIGLEC12, SIGLEC14, SIGLEC6, SIGLEC1, SIGLEC15, TMEM25 |
| Tissue | ovary, adrenal.gland, spleen |
| Tissue Specificity | Expressed by macrophages in various tissues including Kupffer cells. Also found in brain microglia. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Membrane; Single-pass type I membrane protein. |
| Mouse PG classification | NA |
| click here to return to the previous page | |