| Gene Information | |
|---|---|
| Gene Name | CEP43 |
| Organism | Homo sapiens (Human) |
| Gene Length | 399 |
| Protein Names | Centrosomal protein 43 (FGFR1 oncogene partner) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1714 ( ENSG00000213066 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | O95684 |
| Gene Card | CEP43 |
| Uniprot ID | O95684 |
| Pfam | PF09398 |
| In ASD | no |
| Allosteric Prediction | yes (0.081189474) |
| Ortholog in Animals | Alpaca_ CEP43 ( ortholog_one2one ) Dog_ CEP43 ( ortholog_one2one ) GuineaPig_ CEP43 ( ortholog_one2one ) Macaque_ CEP43 ( ortholog_one2one ) Mouse_ Cep43 ( ortholog_one2one ) Pig_ CEP43 ( ortholog_one2one ) Rat_ Cep43 ( ortholog_one2one ) Rabbit_ CEP43 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Ubiquitous. Highly expressed in heart, liver, muscle, kidney, intestine, colon, adrenal gland, prostate, testis, and pancreas. {ECO:0000269|PubMed:9949182}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.043478(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | 2D68 (X-ray 1.60A ) |
| DBSNP | rs34617108 rs17856382 |
| Subcellular location [CC] | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:14654843, ECO:0000269|PubMed:16314388, ECO:0000269|PubMed:16690081, ECO:0000269|PubMed:28659385}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000269|PubMed:28428259, ECO:0000269|PubMed:28625565, ECO:0000269|PubMed:28659385}. Cytoplasm, cytoskeleton, cilium basal body {ECO:0000269|PubMed:28659385}. Note=Associated with gamma-tubulin (PubMed:16314388). Localizes on both mother and daughter centrioles (PubMed:28625565, PubMed:28428259). Localizes to an axial position on the mother centriole (PubMed:28625565). Localizes to the distal end of the centriole partly on the subdistal appendage region (PubMed:28659385). {ECO:0000269|PubMed:16314388, ECO:0000269|PubMed:28428259, ECO:0000269|PubMed:28625565, ECO:0000269|PubMed:28659385}. |
| Mouse PG classification | NA |
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