Gene Information
Gene NameBRF2
OrganismHomo sapiens (Human)
Gene Length419
Protein NamesTranscription factor IIIB 50 kDa subunit (TFIIIB50) (hTFIIIB50) (B-related factor 2) (BRF-2) (hBRFU)
Target NameNA
Target TypeNA
Gene Age645 ( ENSG00000104221 )
Evolutionary StageEumetazoa
AlphaFoldDBQ9HAW0
Gene CardBRF2
Uniprot IDQ9HAW0
PfamPF08271
In ASDno
Allosteric Predictionno (-0.792314061)
Ortholog in AnimalsAlpaca_ BRF2 ( ortholog_one2one )
Dog_ BRF2 ( ortholog_one2one )
GuineaPig_ BRF2 ( ortholog_one2one )
Macaque_ BRF2 ( ortholog_one2one )
Mouse_ Brf2 ( ortholog_one2one )
Pig_ BRF2 ( ortholog_one2one )
Rat_ Brf2 ( ortholog_one2one )
Rabbit_ BRF2 ( ortholog_one2one )
OhnologsNA
ParalogsBRF1, GTF2B
TissueNA
Tissue SpecificityNA
Pharmacological Animal ModelsNULL(Chimpanzee);NULL(Mouse);0.001000(Rat);0.034783(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 4ROC  (X-ray  1.90A  4ROD  (X-ray  2.70A  4ROE  (X-ray  2.20A  5N9G  (X-ray  2.70A 
DBSNP NA 
Subcellular location [CC]Nucleus {ECO:0000269|PubMed:17505538}.
Mouse PG classificationNA
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