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Gene Information
Gene Name
BRD1
Organism
Homo sapiens (Human)
Gene Length
1058
Protein Names
Bromodomain-containing protein 1 (BR140-like protein) (Bromodomain and PHD finger-containing protein 2)
Target Name
NA
Target Type
NA
Gene Age
680 ( ENSG00000100425 )
Evolutionary Stage
Eukaryota
AlphaFoldDB
O95696
Gene Card
BRD1
Uniprot ID
O95696
Pfam
PF00439; PF10513; PF00855
In ASD
no
Allosteric Prediction
no (-0.193536432)
Ortholog in Animals
Alpaca_ BRD1 ( ortholog_one2one )
Dog_ BRD1 ( ortholog_one2one )
GuineaPig_ BRD1 ( ortholog_one2one )
Macaque_ BRD1 ( ortholog_one2one )
Mouse_ Brd1 ( ortholog_one2one )
Pig_ BRD1 ( ortholog_one2one )
Rat_ Brd1 ( ortholog_one2one )
Rabbit_ BRD1 ( ortholog_one2one )
Ohnologs
BRPF3, BRPF1
Paralogs
MLLT10, JADE3, JADE2, BRPF1, BRPF3, PHF14, MLLT6, JADE1
Tissue
NA
Tissue Specificity
Highly expressed in testis. {ECO:0000269|PubMed:10602503}.
Pharmacological Animal Models
NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);NULL(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB
2KU3
(NMR
-
)
2L43
(NMR
-
)
2LQ6
(NMR
-
)
3LYI
(X-ray
2.10A
)
3RCW
(X-ray
2.21A
)
4Z02
(X-ray
1.87A
)
5AME
(X-ray
1.58A
)
5AMF
(X-ray
1.75A
)
5FG6
(X-ray
1.10A
)
5GK9
(X-ray
2.40A
)
5N49
(X-ray
1.94A
)
5PNX
(X-ray
1.47A
)
5PNY
(X-ray
1.48A
)
5PNZ
(X-ray
1.56A
)
5PO0
(X-ray
1.46A
)
5PO1
(X-ray
1.52A
)
5PO2
(X-ray
1.67A
)
5PO3
(X-ray
1.70A
)
5PO4
(X-ray
1.49A
)
5PO5
(X-ray
1.44A
)
5PO6
(X-ray
1.61A
)
5PO7
(X-ray
1.50A
)
5PO8
(X-ray
1.50A
)
5PO9
(X-ray
2.12A
)
5POA
(X-ray
1.62A
)
5POB
(X-ray
1.78A
)
5POC
(X-ray
1.48A
)
5POD
(X-ray
1.56A
)
5POE
(X-ray
1.52A
)
5POF
(X-ray
2.27A
)
5POG
(X-ray
1.77A
)
5POH
(X-ray
1.61A
)
5POI
(X-ray
2.37A
)
5POJ
(X-ray
1.62A
)
5POK
(X-ray
1.56A
)
5POL
(X-ray
1.62A
)
5POM
(X-ray
1.54A
)
5PON
(X-ray
1.52A
)
5POO
(X-ray
1.50A
)
5POP
(X-ray
1.58A
)
5POQ
(X-ray
1.97A
)
5POR
(X-ray
1.58A
)
5POS
(X-ray
1.75A
)
5POT
(X-ray
1.63A
)
5POU
(X-ray
1.43A
)
5POV
(X-ray
1.57A
)
5POW
(X-ray
1.77A
)
5POX
(X-ray
1.75A
)
5POY
(X-ray
1.76A
)
5POZ
(X-ray
1.50A
)
5PP0
(X-ray
1.61A
)
5PP1
(X-ray
2.35A
)
5PP2
(X-ray
1.61A
)
5PP3
(X-ray
2.58A
)
5PP4
(X-ray
1.92A
)
5PP5
(X-ray
1.87A
)
5PP6
(X-ray
1.52A
)
5PP7
(X-ray
1.52A
)
5PP8
(X-ray
1.74A
)
5PP9
(X-ray
1.82A
)
5PPA
(X-ray
1.91A
)
5PPB
(X-ray
1.48A
)
5PPC
(X-ray
1.61A
)
5PPD
(X-ray
1.67A
)
5PPE
(X-ray
1.46A
)
5PPF
(X-ray
1.64A
)
5PPG
(X-ray
1.55A
)
5PPH
(X-ray
1.89A
)
5PPI
(X-ray
1.56A
)
5PPJ
(X-ray
1.61A
)
5PPK
(X-ray
1.87A
)
5PPL
(X-ray
1.63A
)
5PPM
(X-ray
1.87A
)
5PPN
(X-ray
1.80A
)
5PPO
(X-ray
1.84A
)
5PPP
(X-ray
1.68A
)
5PPQ
(X-ray
1.70A
)
5PPR
(X-ray
2.69A
)
5PPS
(X-ray
1.53A
)
5PPT
(X-ray
1.61A
)
5PPU
(X-ray
1.63A
)
5PPV
(X-ray
1.70A
)
5PPW
(X-ray
1.45A
)
5PPX
(X-ray
1.44A
)
5PPY
(X-ray
1.45A
)
5PPZ
(X-ray
1.55A
)
5PQ0
(X-ray
1.81A
)
5PQ1
(X-ray
1.55A
)
5PQ2
(X-ray
1.47A
)
5PQ3
(X-ray
1.72A
)
5PQ4
(X-ray
1.63A
)
5PQ5
(X-ray
1.60A
)
5PQ6
(X-ray
1.64A
)
5PQ7
(X-ray
1.56A
)
5PQ8
(X-ray
1.65A
)
5PQ9
(X-ray
1.60A
)
5PQA
(X-ray
1.78A
)
5PQB
(X-ray
1.58A
)
5PQC
(X-ray
1.45A
)
5PQD
(X-ray
1.65A
)
5PQE
(X-ray
1.53A
)
5PQF
(X-ray
1.65A
)
5PQG
(X-ray
1.82A
)
5PQH
(X-ray
1.52A
)
5PQI
(X-ray
1.33A
)
5PQJ
(X-ray
1.59A
)
5PQK
(X-ray
1.58A
)
5PQL
(X-ray
1.52A
)
5PQM
(X-ray
2.56A
)
5PQN
(X-ray
2.00A
)
5PQO
(X-ray
1.75A
)
5PQP
(X-ray
1.97A
)
5PQQ
(X-ray
2.30A
)
5PQR
(X-ray
2.43A
)
5PQS
(X-ray
1.82A
)
5PQT
(X-ray
1.89A
)
5PQU
(X-ray
2.00A
)
5PQV
(X-ray
1.97A
)
5PQW
(X-ray
2.00A
)
5PQX
(X-ray
1.95A
)
5PQY
(X-ray
1.89A
)
5PQZ
(X-ray
2.58A
)
5PR0
(X-ray
2.23A
)
5PR1
(X-ray
2.10A
)
5PR2
(X-ray
2.10A
)
5PR4
(X-ray
1.82A
)
5PR5
(X-ray
1.95A
)
5PR6
(X-ray
1.80A
)
5PR7
(X-ray
1.80A
)
5PR8
(X-ray
1.92A
)
5PR9
(X-ray
1.82A
)
5PRA
(X-ray
1.87A
)
5PRB
(X-ray
2.23A
)
5PRD
(X-ray
1.90A
)
5PRE
(X-ray
1.73A
)
5PRF
(X-ray
1.82A
)
5PRG
(X-ray
2.68A
)
5PRH
(X-ray
1.95A
)
5PRI
(X-ray
1.90A
)
5PRJ
(X-ray
2.17A
)
5PRK
(X-ray
2.23A
)
5PRL
(X-ray
1.75A
)
5PRM
(X-ray
3.58A
)
5PRO
(X-ray
1.55A
)
5PRP
(X-ray
1.45A
)
5PRQ
(X-ray
1.68A
)
5PRR
(X-ray
1.63A
)
5PRS
(X-ray
1.72A
)
5PRT
(X-ray
1.89A
)
5PRU
(X-ray
1.58A
)
5PRV
(X-ray
1.62A
)
5PRW
(X-ray
1.65A
)
5PRX
(X-ray
1.87A
)
5PRY
(X-ray
1.80A
)
5PRZ
(X-ray
1.62A
)
5PS0
(X-ray
1.68A
)
5PS1
(X-ray
1.71A
)
5PS2
(X-ray
1.55A
)
5PS3
(X-ray
1.93A
)
5PS4
(X-ray
1.70A
)
5PS5
(X-ray
2.15A
)
5PS6
(X-ray
1.52A
)
5PS7
(X-ray
2.21A
)
5PS8
(X-ray
1.93A
)
5PS9
(X-ray
1.71A
)
5PSA
(X-ray
1.64A
)
5PSB
(X-ray
1.62A
)
5PSC
(X-ray
1.68A
)
5PSD
(X-ray
1.63A
)
5PSE
(X-ray
2.19A
)
5PSF
(X-ray
2.31A
)
5PSG
(X-ray
1.55A
)
5PSH
(X-ray
3.43A
)
5PSI
(X-ray
1.62A
)
5PSJ
(X-ray
1.38A
)
5PSK
(X-ray
1.38A
)
5PSL
(X-ray
1.39A
)
5PSM
(X-ray
1.53A
)
5PSN
(X-ray
1.48A
)
5PSO
(X-ray
1.55A
)
5PSP
(X-ray
1.58A
)
5PSQ
(X-ray
1.43A
)
5PSR
(X-ray
1.59A
)
5PSS
(X-ray
1.59A
)
5PST
(X-ray
1.39A
)
5PSU
(X-ray
1.56A
)
5PSV
(X-ray
1.53A
)
5PSW
(X-ray
1.53A
)
5PSX
(X-ray
1.59A
)
5PSY
(X-ray
1.82A
)
5PSZ
(X-ray
1.53A
)
5PT0
(X-ray
1.43A
)
5PT1
(X-ray
1.54A
)
5PT2
(X-ray
1.52A
)
5PT3
(X-ray
1.70A
)
5PT4
(X-ray
1.54A
)
5PT5
(X-ray
1.76A
)
5PT6
(X-ray
1.53A
)
5PT7
(X-ray
1.55A
)
5PT8
(X-ray
1.66A
)
5PT9
(X-ray
1.47A
)
5PTA
(X-ray
2.19A
)
5PTB
(X-ray
1.88A
)
5PTC
(X-ray
1.78A
)
5PTE
(X-ray
1.63A
)
5PTF
(X-ray
1.49A
)
5PTG
(X-ray
1.46A
)
5PTH
(X-ray
1.56A
)
5PTJ
(X-ray
1.69A
)
5PTK
(X-ray
1.48A
)
5PTL
(X-ray
1.53A
)
5PTM
(X-ray
1.41A
)
5PTN
(X-ray
1.47A
)
5PTO
(X-ray
1.67A
)
5PTQ
(X-ray
1.49A
)
5PTR
(X-ray
1.52A
)
5PTS
(X-ray
1.45A
)
5PTT
(X-ray
1.47A
)
5PTU
(X-ray
1.69A
)
5PTV
(X-ray
1.70A
)
5PTW
(X-ray
1.82A
)
5PTX
(X-ray
1.60A
)
5PTY
(X-ray
2.10A
)
5PTZ
(X-ray
1.51A
)
5PU0
(X-ray
1.89A
)
5PU1
(X-ray
1.73A
)
5PU2
(X-ray
1.59A
)
5PU3
(X-ray
2.37A
)
5PU4
(X-ray
1.55A
)
5PU5
(X-ray
1.55A
)
5PU6
(X-ray
1.74A
)
5PU7
(X-ray
1.62A
)
5PU8
(X-ray
1.55A
)
5PU9
(X-ray
1.56A
)
5PUA
(X-ray
1.63A
)
5PUB
(X-ray
2.23A
)
5PUC
(X-ray
1.64A
)
5PUD
(X-ray
2.01A
)
5PUE
(X-ray
1.70A
)
5PUF
(X-ray
1.82A
)
5PUG
(X-ray
2.00A
)
5PUH
(X-ray
1.92A
)
5PUI
(X-ray
1.51A
)
5PUJ
(X-ray
1.90A
)
5PUK
(X-ray
1.64A
)
5PUL
(X-ray
1.95A
)
5PUM
(X-ray
2.15A
)
5PUN
(X-ray
1.84A
)
5PUO
(X-ray
2.06A
)
5PUP
(X-ray
1.60A
)
5PUQ
(X-ray
1.70A
)
5PUR
(X-ray
1.73A
)
5PUS
(X-ray
1.67A
)
5PUT
(X-ray
2.32A
)
5PUU
(X-ray
1.69A
)
5PUV
(X-ray
1.69A
)
5PUW
(X-ray
1.82A
)
5PUX
(X-ray
1.51A
)
5PUY
(X-ray
2.01A
)
5PUZ
(X-ray
1.49A
)
5PV0
(X-ray
1.76A
)
5PV1
(X-ray
1.73A
)
5PV2
(X-ray
1.63A
)
5PV3
(X-ray
1.48A
)
5PV4
(X-ray
1.58A
)
5PV5
(X-ray
1.68A
)
5PV6
(X-ray
1.62A
)
5PV7
(X-ray
1.58A
)
5PV8
(X-ray
1.49A
)
5PV9
(X-ray
1.67A
)
5PVA
(X-ray
1.98A
)
5PVB
(X-ray
1.53A
)
5PVC
(X-ray
1.56A
)
5PVD
(X-ray
1.53A
)
5PVE
(X-ray
2.29A
)
5PVF
(X-ray
1.71A
)
5PVG
(X-ray
1.69A
)
5PVH
(X-ray
1.69A
)
5PVI
(X-ray
2.19A
)
5PVJ
(X-ray
1.57A
)
5PVK
(X-ray
1.58A
)
5PVL
(X-ray
1.53A
)
5PVM
(X-ray
1.65A
)
5PVN
(X-ray
1.63A
)
5PVO
(X-ray
1.96A
)
5PVP
(X-ray
1.69A
)
5PVQ
(X-ray
1.61A
)
5PVR
(X-ray
1.57A
)
5PVS
(X-ray
1.55A
)
5PVT
(X-ray
1.48A
)
5PVU
(X-ray
3.01A
)
5PVV
(X-ray
1.80A
)
5PVW
(X-ray
2.18A
)
5PVX
(X-ray
1.74A
)
5PVY
(X-ray
2.49A
)
5PVZ
(X-ray
1.64A
)
5PW0
(X-ray
2.13A
)
5PW1
(X-ray
1.57A
)
5PW2
(X-ray
2.32A
)
5PW3
(X-ray
2.21A
)
5PW4
(X-ray
1.91A
)
5PW5
(X-ray
2.09A
)
5PW6
(X-ray
2.75A
)
5PW7
(X-ray
1.85A
)
5PW8
(X-ray
2.08A
)
5PW9
(X-ray
3.44A
)
5PWA
(X-ray
1.86A
)
5PWB
(X-ray
2.09A
)
6IN2
(X-ray
1.75A
)
6MAJ
(X-ray
2.14A
)
6MAK
(X-ray
2.13A
)
7D0O
(X-ray
2.51A
)
7D0P
(X-ray
1.80A
)
7D0Q
(X-ray
2.21A
)
7D0R
(X-ray
1.95A
)
7D0S
(X-ray
2.30A
)
7LH9
(X-ray
2.60A
)
DBSNP
rs11549978
rs12157714
rs35331092
Subcellular location [CC]
Nucleus {ECO:0000269|PubMed:21753189, ECO:0000269|PubMed:21880731}. Chromosome {ECO:0000269|PubMed:21753189, ECO:0000269|PubMed:28334966}. Note=Localizes to transcription start sites. {ECO:0000269|PubMed:21753189, ECO:0000269|PubMed:28334966}.
Mouse PG classification
NA
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