| Gene Information | |
|---|---|
| Gene Name | PRODH |
| Organism | Homo sapiens (Human) |
| Gene Length | 600 |
| Protein Names | Proline dehydrogenase 1, mitochondrial (EC 1.5.5.2) (Proline oxidase) (Proline oxidase 2) (p53-induced gene 6 protein) |
| Target Name | proline dehydrogenase 1, mitochondrial |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000100033 ) 645 ( ENSG00000277196 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | O43272 |
| Gene Card | PRODH |
| Uniprot ID | O43272 |
| Pfam | PF01619 |
| In ASD | no |
| Allosteric Prediction | yes (0.068642986) |
| Ortholog in Animals | Mouse_ Prodh ( ortholog_one2many ) Rat_ Prodh1 ( ortholog_one2many ) |
| Ohnologs | NA |
| Paralogs | PRODH2 |
| Tissue | NA |
| Tissue Specificity | Expressed in lung, skeletal muscle and brain, to a lesser extent in heart and kidney, and weakly in liver, placenta and pancreas. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs181332931 rs2008720 rs3815655 rs146648839 rs761544165 rs386819653 rs4819756 rs5747933 rs137852934 rs3970555 rs2238731 rs2904552 rs2904551 rs765090516 rs3970559 rs1807467 rs2870984 rs2870983 rs139903009 rs193919334 rs450046 |
| Subcellular location [CC] | Mitochondrion matrix. |
| Mouse PG classification | NA |
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