| Gene Information | |
|---|---|
| Gene Name | PPFIA4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1185 |
| Protein Names | Liprin-alpha-4 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-4) (PTPRF-interacting protein alpha-4) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000143847 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | O75335 |
| Gene Card | PPFIA4 |
| Uniprot ID | O75335 |
| Pfam | PF00536; PF07647 |
| In ASD | no |
| Allosteric Prediction | no (-0.207458377) |
| Ortholog in Animals | Alpaca_ PPFIA4 ( ortholog_one2one ) Dog_ PPFIA4 ( ortholog_one2one ) GuineaPig_ PPFIA4 ( ortholog_one2one ) Macaque_ PPFIA4 ( ortholog_one2one ) Mouse_ Ppfia4 ( ortholog_one2one ) Pig_ PPFIA4 ( ortholog_one2one ) Rat_ Ppfia4 ( ortholog_one2one ) Rabbit_ PPFIA4 ( ortholog_one2one ) |
| Ohnologs | PPFIA2, PPFIA3 |
| Paralogs | PPFIBP1, PPFIBP2, PPFIA2, PPFIA1, PPFIA3 |
| Tissue | brain, heart, cerebellar.hemisphere, cerebellum |
| Tissue Specificity | Expressed only in the heart, brain, and skeletal muscle. {ECO:0000269|PubMed:9624153}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000250}. Cell surface {ECO:0000250}. Note=Colocalizes with PTPRF at the cell surface. {ECO:0000250}. |
| Mouse PG classification | NA |
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