| Gene Information | |
|---|---|
| Gene Name | NSUN4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 384 |
| Protein Names | 5-methylcytosine rRNA methyltransferase NSUN4 (EC 2.1.1.-) (5-methylcytosine tRNA methyltransferase NSUN4) (EC 2.1.1.-) (NOL1/NOP2/Sun domain family member 4) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 886 ( ENSG00000117481 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q96CB9 |
| Gene Card | NSUN4 |
| Uniprot ID | Q96CB9 |
| Pfam | PF01189 |
| In ASD | no |
| Allosteric Prediction | no (-1.513702531) |
| Ortholog in Animals | Alpaca_ NSUN4 ( ortholog_one2one ) GuineaPig_ NSUN4 ( ortholog_one2one ) Pig_ NSUN4 ( ortholog_one2one ) Rat_ Nsun4 ( ortholog_one2one ) Rabbit_ NSUN4 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NSUN3, NSUN2 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.003490(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4FP9 (X-ray 2.90A ) 4FZV (X-ray 2.00A ) 7O9K (EM 3.10A ) 7O9M (EM 2.50A ) 7ODR (EM 2.90A ) 7ODS (EM 3.10A ) 7ODT (EM 3.10A ) 7OF0 (EM 2.20A ) 7OF3 (EM 2.70A ) 7OF5 (EM 2.90A ) 7OF7 (EM 2.50A ) 7OIC (EM 3.10A ) 7PD3 (EM 3.40A ) |
| DBSNP | rs3737744 rs17102152 rs13374337 rs9865 |
| Subcellular location [CC] | Mitochondrion {ECO:0000269|PubMed:21531335, ECO:0000269|PubMed:22949673, ECO:0000269|PubMed:23022348}. |
| Mouse PG classification | NA |
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