Gene Information
Gene NameBPHL
OrganismHomo sapiens (Human)
Gene Length291
Protein NamesValacyclovir hydrolase (VACVase) (Valacyclovirase) (EC 3.1.-.-) (Biphenyl hydrolase-like protein) (Biphenyl hydrolase-related protein) (Bph-rp) (Breast epithelial mucin-associated antigen) (MCNAA)
Target Namevalacyclovir hydrolase
Target TypeNA
Gene Age454 ( ENSG00000137274 )
Evolutionary StageCellular_organisms
AlphaFoldDBQ86WA6
Gene CardBPHL
Uniprot IDQ86WA6
PfamPF00561
In ASDno
Allosteric Predictionyes (0.158007083)
Ortholog in AnimalsAlpaca_ BPHL ( ortholog_one2one )
Dog_ BPHL ( ortholog_one2one )
GuineaPig_ BPHL ( ortholog_one2one )
Macaque_ BPHL ( ortholog_one2one )
Mouse_ Bphl ( ortholog_one2one )
Pig_ BPHL ( ortholog_one2one )
Rat_ Bphl ( ortholog_one2one )
Rabbit_ BPHL ( ortholog_one2one )
OhnologsNA
ParalogsSERHL2, MEST, EPHX4, ABHD6, ABHD8, ABHD11, EPHX2, ABHD5, ABHD4, ABHD14B, ABHD14A, EPHX3
TissueNA
Tissue SpecificityExpressed at high levels in liver and kidney and lower levels in heart, intestine and skeletal muscle. {ECO:0000269|PubMed:7759552}.
Pharmacological Animal ModelsNULL(Chimpanzee);NULL(Mouse);0.002490(Rat);NULL(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 2OCG  (X-ray  1.75A  2OCI  (X-ray  1.90A  2OCK  (X-ray  1.85A  2OCL  (X-ray  1.90A 
DBSNP NA 
Subcellular location [CC]NA
Mouse PG classificationNA
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