| Gene Information | |
|---|---|
| Gene Name | BPHL |
| Organism | Homo sapiens (Human) |
| Gene Length | 291 |
| Protein Names | Valacyclovir hydrolase (VACVase) (Valacyclovirase) (EC 3.1.-.-) (Biphenyl hydrolase-like protein) (Biphenyl hydrolase-related protein) (Bph-rp) (Breast epithelial mucin-associated antigen) (MCNAA) |
| Target Name | valacyclovir hydrolase |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000137274 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q86WA6 |
| Gene Card | BPHL |
| Uniprot ID | Q86WA6 |
| Pfam | PF00561 |
| In ASD | no |
| Allosteric Prediction | yes (0.158007083) |
| Ortholog in Animals | Alpaca_ BPHL ( ortholog_one2one ) Dog_ BPHL ( ortholog_one2one ) GuineaPig_ BPHL ( ortholog_one2one ) Macaque_ BPHL ( ortholog_one2one ) Mouse_ Bphl ( ortholog_one2one ) Pig_ BPHL ( ortholog_one2one ) Rat_ Bphl ( ortholog_one2one ) Rabbit_ BPHL ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | SERHL2, MEST, EPHX4, ABHD6, ABHD8, ABHD11, EPHX2, ABHD5, ABHD4, ABHD14B, ABHD14A, EPHX3 |
| Tissue | NA |
| Tissue Specificity | Expressed at high levels in liver and kidney and lower levels in heart, intestine and skeletal muscle. {ECO:0000269|PubMed:7759552}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.002490(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2OCG (X-ray 1.75A ) 2OCI (X-ray 1.90A ) 2OCK (X-ray 1.85A ) 2OCL (X-ray 1.90A ) |
| DBSNP | NA |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
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