| Gene Information | |
|---|---|
| Gene Name | BOM |
| Organism | Homo sapiens (Human) |
| Gene Length | 625 |
| Protein Names | Grainyhead-like protein 2 homolog (Brother of mammalian grainyhead) (Transcription factor CP2-like 3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q6ISB3 |
| Gene Card | GRHL2 |
| Uniprot ID | Q6ISB3 |
| Pfam | PF04516 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in keratinocytes (at protein level). Highly expressed in placenta, prostate, brain and kidney. Lower-level expression in a variety of epithelial tissues such as thymus, lung, salivary gland, mammary gland and digestive tract. Expressed in the cochlear. Expressed in corneal epithelial cells, but not in the endothelium or stroma (PubMed:29499165). {ECO:0000269|PubMed:12175488, ECO:0000269|PubMed:12393799, ECO:0000269|PubMed:20978075, ECO:0000269|PubMed:25152456, ECO:0000269|PubMed:29499165}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5MR7 (X-ray 2.50A ) |
| DBSNP | rs587777737 rs3779617 rs587777738 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:20938050, ECO:0000269|PubMed:25152456, ECO:0000269|PubMed:29499165}. Membrane {ECO:0000269|PubMed:25152456}. Note=detected at cell-cell contact areas. {ECO:0000269|PubMed:25152456}. |
| Mouse PG classification | NA |
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