Gene Information
Gene NameBNIPXL
OrganismHomo sapiens (Human)
Gene Length3088
Protein NamesProtein prune homolog 2 (BNIP2 motif-containing molecule at the C-terminal region 1)
Target NameNA
Target TypeNA
Gene AgeNA
Evolutionary StageNA
AlphaFoldDBNA
Gene CardPRUNE2
Uniprot IDQ8WUY3
PfamPF12496; PF13716; PF02833
In ASDno
Allosteric PredictionNA
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityA high level of expression seen in the nervous system (brain, cerebellum and spinal cord) as well as adrenal gland. Expressed at high levels in noneuroblastoma, rhabdomyosarcoma, melanoma and some osteosarcoma cell lines, whereas at only low levels in cancer cell lines of liver, breast, thyroid and colon. Expression is significantly higher in favorable tumors than aggressive ones. {ECO:0000269|PubMed:16288218}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs375315668 
Subcellular location [CC]Cytoplasm {ECO:0000269|PubMed:16288218}.
Mouse PG classificationNA
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