| Gene Information | |
|---|---|
| Gene Name | BNC1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 994 |
| Protein Names | Zinc finger protein basonuclin-1 |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 810 ( ENSG00000169594 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q01954 |
| Gene Card | BNC1 |
| Uniprot ID | Q01954 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | no (-0.964139827) |
| Ortholog in Animals | Alpaca_ BNC1 ( ortholog_one2one ) Dog_ BNC1 ( ortholog_one2one ) GuineaPig_ BNC1 ( ortholog_one2one ) Macaque_ BNC1 ( ortholog_one2one ) Mouse_ Bnc1 ( ortholog_one2one ) Pig_ BNC1 ( ortholog_one2one ) Rat_ Bnc1 ( ortholog_one2one ) Rabbit_ BNC1 ( ortholog_one2one ) |
| Ohnologs | BNC2 |
| Paralogs | BNC2 |
| Tissue | testis, esophagus.mucosa |
| Tissue Specificity | In epidermis, primarily detected in cells of the basal or immediately suprabasal layers (at protein level) (PubMed:16891417). In hair follicles, mainly expressed in the outer root sheath (at protein level) (PubMed:8034748). Expressed in epidermis, testis and foreskin, and to a lower extent in thymus, spleen, mammary glands, placenta, brain and heart (PubMed:9687312). Expressed in the ovary, notably in oocytes (PubMed:30010909). {ECO:0000269|PubMed:16891417, ECO:0000269|PubMed:30010909, ECO:0000269|PubMed:8034748, ECO:0000269|PubMed:9687312}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs149100994 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:16891417, ECO:0000269|PubMed:30010909, ECO:0000269|PubMed:8034748, ECO:0000269|PubMed:9223293}. Cytoplasm {ECO:0000269|PubMed:9223293}. Nucleus, nucleoplasm {ECO:0000269|PubMed:16891417}. Note=Relocates to the midpiece of the flagellum during late spermiogenesis in spermatids. {ECO:0000250|UniProtKB:O35914}. |
| Mouse PG classification | NA |
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