| Gene Information | |
|---|---|
| Gene Name | GRAP |
| Organism | Homo sapiens (Human) |
| Gene Length | 217 |
| Protein Names | GRB2-related adapter protein |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000154016 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q13588 |
| Gene Card | GRAP |
| Uniprot ID | Q13588 |
| Pfam | PF00017; PF00018 |
| In ASD | no |
| Allosteric Prediction | no (-0.686771505) |
| Ortholog in Animals | GuineaPig_ GRAP ( ortholog_one2one ) Mouse_ Grap ( ortholog_one2many ) Rat_ Grap ( ortholog_one2many ) Rabbit_ GRAP ( ortholog_one2one ) |
| Ohnologs | GRB2 |
| Paralogs | GRAPL, SLA, DAPP1, SH2D5, NCK1, GRB2, GRAP2, NCK2, SLA2 |
| Tissue | spleen |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);0.04(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs370564476 |
| Subcellular location [CC] | Membrane {ECO:0000250|UniProtKB:Q08012}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q08012}. Synapse {ECO:0000250|UniProtKB:Q08012}. Note=Localizes at the presynaptic terminal. {ECO:0000250|UniProtKB:Q08012}. |
| Mouse PG classification | NA |
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