| Gene Information | |
|---|---|
| Gene Name | BMP14 |
| Organism | Homo sapiens (Human) |
| Gene Length | 501 |
| Protein Names | Growth/differentiation factor 5 (GDF-5) (Bone morphogenetic protein 14) (BMP-14) (Cartilage-derived morphogenetic protein 1) (CDMP-1) (Lipopolysaccharide-associated protein 4) (LAP-4) (LPS-associated protein 4) (Radotermin) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | P43026 |
| Gene Card | GDF5 |
| Uniprot ID | P43026 |
| Pfam | PF00019; PF00688 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Predominantly expressed in long bones during embryonic development. Expressed in monocytes (at protein level). {ECO:0000269|PubMed:11276205}. |
| Pharmacological Animal Models | 0.000730(Chimpanzee);0.001000(Mouse);0.001000(Rat);0.071429(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1WAQ (X-ray 2.28A ) 2BHK (X-ray 2.40A ) 3EVS (X-ray 2.10A ) 3QB4 (X-ray 2.28A ) 5HK5 (X-ray 2.90A ) 6Z3G (X-ray 2.78A ) 6Z3H (X-ray 3.16A ) 6Z3J (X-ray 1.65A ) 6Z3L (X-ray 2.51A ) 6Z3M (X-ray 5.50A ) |
| DBSNP | rs34534075 rs28936397 rs224331 rs121909349 rs121909350 rs397514668 rs397514519 rs74315387 rs121909351 rs74315388 rs28936683 rs121909347 rs74315389 |
| Subcellular location [CC] | Secreted {ECO:0000269|PubMed:11276205}. Cell membrane {ECO:0000269|PubMed:11276205}. |
| Mouse PG classification | NA |
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