| Gene Information | |
|---|---|
| Gene Name | BMI1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 326 |
| Protein Names | Polycomb complex protein BMI-1 (Polycomb group RING finger protein 4) (RING finger protein 51) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000168283 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P35226 |
| Gene Card | BMI1 |
| Uniprot ID | P35226 |
| Pfam | PF16207 |
| In ASD | no |
| Allosteric Prediction | yes (0.177180145) |
| Ortholog in Animals | Alpaca_ BMI1 ( ortholog_one2one ) Dog_ COMMD3 ( ortholog_one2one ) GuineaPig_ BMI1 ( ortholog_one2one ) Macaque_ BMI1 ( ortholog_one2one ) Mouse_ Bmi1 ( ortholog_one2one ) Pig_ BMI1 ( ortholog_one2one ) Rat_ Bmi1 ( ortholog_one2one ) |
| Ohnologs | PCGF5, PCGF6, PCGF3 |
| Paralogs | PCGF3, RNF2, PCGF5, PCGF6, RING1, PCGF1, PCGF2 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.168134(Rat);0.046896(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2H0D (X-ray 2.50A ) 2NA1 (NMR - ) 3RPG (X-ray 2.65A ) 4R8P (X-ray 3.28A ) 5FR6 (X-ray 2.51A ) 6WI7 (X-ray 1.70A ) 6WI8 (X-ray 3.09A ) 7ND1 (NMR - ) |
| DBSNP | rs1042059 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:16882984, ECO:0000269|PubMed:9199346}. Cytoplasm {ECO:0000269|PubMed:16882984}. |
| Mouse PG classification | NA |
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