| Gene Information | |
|---|---|
| Gene Name | BM-043 |
| Organism | Homo sapiens (Human) |
| Gene Length | 782 |
| Protein Names | Calcium-independent phospholipase A2-gamma (EC 3.1.1.-) (EC 3.1.1.5) (Intracellular membrane-associated calcium-independent phospholipase A2 gamma) (iPLA2-gamma) (PNPLA-gamma) (Patatin-like phospholipase domain-containing protein 8) (iPLA2-2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q9NP80 |
| Gene Card | PNPLA8 |
| Uniprot ID | Q9NP80 |
| Pfam | PF01734 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in parenchymal tissues including heart, skeletal muscle, placenta, brain, liver and pancreas. Also expressed in bronchial epithelial cells and kidney. Highest expression is observed in skeletal muscle and heart. {ECO:0000269|PubMed:10744668, ECO:0000269|PubMed:10833412, ECO:0000269|PubMed:15629460, ECO:0000269|PubMed:15695510, ECO:0000269|PubMed:15908428}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q5XTS1}; Single-pass membrane protein {ECO:0000305|PubMed:10744668, ECO:0000305|PubMed:10833412}. Mitochondrion membrane {ECO:0000305|PubMed:17213206}; Single-pass membrane protein {ECO:0000305|PubMed:10744668, ECO:0000305|PubMed:10833412}. Peroxisome membrane {ECO:0000269|PubMed:15695510}; Single-pass membrane protein {ECO:0000305|PubMed:10744668, ECO:0000305|PubMed:10833412}. |
| Mouse PG classification | NA |
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