| Gene Information | |
|---|---|
| Gene Name | BLOC1S2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 142 |
| Protein Names | Biogenesis of lysosome-related organelles complex 1 subunit 2 (BLOC-1 subunit 2) (Centrosome-associated protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000196072 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q6QNY1 |
| Gene Card | BLOC1S2 |
| Uniprot ID | Q6QNY1 |
| Pfam | PF10046 |
| In ASD | no |
| Allosteric Prediction | no (-1.418726046) |
| Ortholog in Animals | Alpaca_ BLOC1S2 ( ortholog_one2one ) Dog_ BLOC1S2 ( ortholog_one2one ) GuineaPig_ BLOC1S2 ( ortholog_one2one ) Macaque_ BLOC1S2 ( ortholog_one2one ) Mouse_ Bloc1s2 ( ortholog_one2one ) Pig_ BLOC1S2 ( ortholog_one2one ) Rat_ Bloc1s2 ( ortholog_one2one ) Rabbit_ BLOC1S2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | PYROXD2, RETSAT |
| Tissue | NA |
| Tissue Specificity | Isoform 1 and isoform 2 are widely expressed. Expressed in various malignant tumor tissues (at protein level). {ECO:0000269|PubMed:15381421}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.013333(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs33965491 |
| Subcellular location [CC] | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:15381421}. Lysosome membrane {ECO:0000305|PubMed:25898167}. Note=Localizes to the centrosomes in a microtubule-dependent manner. {ECO:0000269|PubMed:15381421}. |
| Mouse PG classification | NA |
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