| Gene Information | |
|---|---|
| Gene Name | GPHB5 |
| Organism | Homo sapiens (Human) |
| Gene Length | 130 |
| Protein Names | Glycoprotein hormone beta-5 (Thyrostimulin subunit beta) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000179600 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q86YW7 |
| Gene Card | GPHB5 |
| Uniprot ID | Q86YW7 |
| Pfam | PF00007 |
| In ASD | no |
| Allosteric Prediction | no (-0.384692971) |
| Ortholog in Animals | Alpaca_ GPHB5 ( ortholog_one2one ) Dog_ GPB5 ( ortholog_one2one ) GuineaPig_ GPHB5 ( ortholog_one2one ) Macaque_ GPHB5 ( ortholog_one2one ) Mouse_ Gphb5 ( ortholog_one2one ) Pig_ GPHB5 ( ortholog_one2one ) Rat_ Gphb5 ( ortholog_one2one ) Rabbit_ GPHB5 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | TSHB, FSHB, CGB2, CGB1, CGB7, CGB5, CGB8, CGB3, LHB |
| Tissue | NA |
| Tissue Specificity | Highly expressed in brain and at low levels in pituitary. Also found in retina, testis and skin but not in pancreas, parotid, kidney, stomach, liver, colon, small intestine, thyroid, brain or adrenal gland. In pituitary, colocalizes with ACTH, suggesting that it is located in corticotrophs. {ECO:0000269|PubMed:12089349, ECO:0000269|PubMed:16210345}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Secreted. |
| Mouse PG classification | NA |
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