| Gene Information | |
|---|---|
| Gene Name | BIS |
| Organism | Homo sapiens (Human) |
| Gene Length | 575 |
| Protein Names | BAG family molecular chaperone regulator 3 (BAG-3) (Bcl-2-associated athanogene 3) (Bcl-2-binding protein Bis) (Docking protein CAIR-1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | O95817 |
| Gene Card | BAG3 |
| Uniprot ID | O95817 |
| Pfam | PF02179; PF00397 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001578(Rat);0.031818(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs35434411 rs387906874 rs141355480 rs145393807 rs774241343 rs2234962 rs61756328 rs121918312 rs397514506 rs117671123 rs78439745 rs144692954 rs11199064 rs3858340 rs397516881 rs397514507 rs387906876 rs763530097 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:26159920}. Cytoplasm {ECO:0000269|PubMed:26159920}. Note=Colocalizes with HSF1 to the nucleus upon heat stress (PubMed:26159920). {ECO:0000269|PubMed:26159920}. |
| Mouse PG classification | NA |
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