| Gene Information | |
|---|---|
| Gene Name | BIRC4BP |
| Organism | Homo sapiens (Human) |
| Gene Length | 301 |
| Protein Names | XIAP-associated factor 1 (BIRC4-binding protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q6GPH4 |
| Gene Card | XAF1 |
| Uniprot ID | Q6GPH4 |
| Pfam | PF18608 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Widely expressed. Expression is frequently down-regulated in cancer cell lines. Isoform 5 is widely expressed. Expressed in placenta (at protein level). {ECO:0000269|PubMed:11175744, ECO:0000269|PubMed:16343440, ECO:0000269|PubMed:17329253, ECO:0000269|PubMed:17570219}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2LXW (NMR - ) |
| DBSNP | rs34195599 rs2271232 rs34625877 rs3736433 |
| Subcellular location [CC] | Cytoplasm. Nucleus. Mitochondrion. Note=Found in the cytoplasm and nucleus of placental syncytiotrophoblasts. Translocates to mitochondria upon TNF-alpha treatment.; [Isoform 1]: Nucleus.; [Isoform 5]: Nucleus. |
| Mouse PG classification | NA |
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