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Gene Information
Gene Name
BHLHE75
Organism
Homo sapiens (Human)
Gene Length
1464
Protein Names
Nuclear receptor coactivator 2 (NCoA-2) (Class E basic helix-loop-helix protein 75) (bHLHe75) (Transcriptional intermediary factor 2) (hTIF2)
Target Name
NA
Target Type
NA
Gene Age
NA
Evolutionary Stage
NA
AlphaFoldDB
Q15596
Gene Card
NCOA2
Uniprot ID
Q15596
Pfam
PF07469; PF16279; PF08815; PF00989; PF08832
In ASD
no
Allosteric Prediction
NA
Ortholog in Animals
NA
Ohnologs
NA
Paralogs
NA
Tissue
NA
Tissue Specificity
NA
Pharmacological Animal Models
NULL(Chimpanzee);0.047921(Mouse);0.088736(Rat);0.081244(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB
1GWQ
(X-ray
2.45A
)
1GWR
(X-ray
2.40A
)
1M2Z
(X-ray
2.50A
)
1MV9
(X-ray
1.90A
)
1MVC
(X-ray
1.90A
)
1MZN
(X-ray
1.90A
)
1P93
(X-ray
2.70A
)
1T63
(X-ray
2.07A
)
1T65
(X-ray
1.66A
)
1UHL
(X-ray
2.90A
)
1YOK
(X-ray
2.50A
)
1ZDT
(X-ray
2.10A
)
1ZDU
(X-ray
2.50A
)
1ZKY
(X-ray
2.25A
)
2AO6
(X-ray
1.89A
)
2B1V
(X-ray
1.80A
)
2B1Z
(X-ray
1.78A
)
2B23
(X-ray
2.10A
)
2FAI
(X-ray
2.10A
)
2G44
(X-ray
2.65A
)
2G5O
(X-ray
2.30A
)
2LDC
(NMR
-
)
2P15
(X-ray
1.94A
)
2P1T
(X-ray
1.80A
)
2P1U
(X-ray
2.20A
)
2P1V
(X-ray
2.20A
)
2Q7J
(X-ray
1.90A
)
2Q7L
(X-ray
1.92A
)
2YJD
(X-ray
1.93A
)
2ZXZ
(X-ray
3.00A
)
2ZY0
(X-ray
2.90A
)
3A9E
(X-ray
2.75A
)
3CLD
(X-ray
2.84A
)
3DZU
(X-ray
3.20A
)
3DZY
(X-ray
3.10A
)
3E00
(X-ray
3.10A
)
3E7C
(X-ray
2.15A
)
3E94
(X-ray
1.90A
)
3ERD
(X-ray
2.03A
)
3FUG
(X-ray
2.00A
)
3GN8
(X-ray
2.50A
)
3K22
(X-ray
2.10A
)
3K23
(X-ray
3.00A
)
3KWY
(X-ray
2.30A
)
3KYT
(X-ray
2.35A
)
3L0E
(X-ray
2.30A
)
3L0J
(X-ray
2.40A
)
3L0L
(X-ray
1.74A
)
3O1D
(X-ray
2.40A
)
3O1E
(X-ray
2.50A
)
3OAP
(X-ray
2.05A
)
3OZJ
(X-ray
2.10A
)
3PCU
(X-ray
2.00A
)
3PLZ
(X-ray
1.75A
)
3Q95
(X-ray
2.05A
)
3R5M
(X-ray
2.80A
)
3UP0
(X-ray
1.60A
)
3UP3
(X-ray
1.25A
)
4CSJ
(X-ray
2.30A
)
4DOS
(X-ray
2.00A
)
4E2J
(X-ray
2.50A
)
4FHH
(X-ray
2.33A
)
4FHI
(X-ray
2.40A
)
4IA1
(X-ray
2.44A
)
4IA2
(X-ray
2.95A
)
4IA3
(X-ray
2.70A
)
4IA7
(X-ray
2.70A
)
4IQR
(X-ray
2.90A
)
4IU7
(X-ray
2.29A
)
4IUI
(X-ray
2.30A
)
4IV2
(X-ray
2.14A
)
4IV4
(X-ray
2.30A
)
4IVW
(X-ray
2.06A
)
4IVY
(X-ray
1.95A
)
4IW6
(X-ray
1.98A
)
4IW8
(X-ray
2.04A
)
4IWC
(X-ray
2.24A
)
4IWF
(X-ray
1.93A
)
4K4J
(X-ray
2.00A
)
4K6I
(X-ray
2.10A
)
4M8E
(X-ray
2.40A
)
4M8H
(X-ray
2.20A
)
4NIE
(X-ray
2.01A
)
4NQA
(X-ray
3.10A
)
4OC7
(X-ray
2.50A
)
4P6W
(X-ray
1.95A
)
4P6X
(X-ray
2.50A
)
4PLD
(X-ray
1.75A
)
4PLE
(X-ray
1.75A
)
4POH
(X-ray
2.30A
)
4POJ
(X-ray
2.00A
)
4PP3
(X-ray
2.00A
)
4PP5
(X-ray
2.00A
)
4PP6
(X-ray
2.20A
)
4PPP
(X-ray
2.69A
)
4PPS
(X-ray
1.93A
)
4PXM
(X-ray
1.90A
)
4Q0A
(X-ray
1.90A
)
4Q13
(X-ray
2.24A
)
4QE6
4QE8
(X-ray
2.62A
)
4RFW
(X-ray
2.40A
)
4RMC
(X-ray
2.70A
)
4RMD
(X-ray
1.90A
)
4RME
(X-ray
2.30A
)
4RUO
(X-ray
2.81A
)
4UDC
(X-ray
2.50A
)
4UDD
(X-ray
1.80A
)
4WG0
(X-ray
1.82A
)
4ZN7
(X-ray
1.93A
)
4ZN9
(X-ray
2.21A
)
4ZNH
(X-ray
1.93A
)
4ZNS
(X-ray
1.86A
)
4ZNT
(X-ray
1.90A
)
4ZNU
(X-ray
2.40A
)
4ZNV
(X-ray
1.77A
)
4ZNW
(X-ray
2.31A
)
4ZO1
(X-ray
3.22A
)
4ZSH
(X-ray
1.80A
)
5APH
(X-ray
1.54A
)
5APJ
(X-ray
2.08A
)
5DI7
(X-ray
2.24A
)
5DID
(X-ray
2.24A
)
5DIE
(X-ray
2.24A
)
5DIG
(X-ray
2.24A
)
5DK9
(X-ray
2.28A
)
5DKB
(X-ray
2.40A
)
5DKE
(X-ray
2.60A
)
5DKG
(X-ray
2.15A
)
5DKS
(X-ray
2.60A
)
5DL4
(X-ray
2.10A
)
5DLR
(X-ray
2.26A
)
5DMC
(X-ray
2.40A
)
5DMF
(X-ray
2.40A
)
5DP0
(X-ray
2.38A
)
5DRJ
(X-ray
2.07A
)
5DRM
(X-ray
2.24A
)
5DTV
(X-ray
2.29A
)
5DU5
(X-ray
2.19A
)
5DUE
(X-ray
2.09A
)
5DUG
(X-ray
2.25A
)
5DUH
(X-ray
2.24A
)
5DVS
(X-ray
2.28A
)
5DVV
(X-ray
2.50A
)
5DWE
(X-ray
1.92A
)
5DWG
(X-ray
2.30A
)
5DWI
(X-ray
2.43A
)
5DWJ
(X-ray
2.00A
)
5DX3
(X-ray
2.09A
)
5DXB
(X-ray
2.08A
)
5DXE
(X-ray
1.50A
)
5DXG
(X-ray
1.86A
)
5DXK
(X-ray
2.23A
)
5DXM
(X-ray
2.37A
)
5DXP
(X-ray
2.20A
)
5DXQ
(X-ray
2.40A
)
5DXR
(X-ray
2.28A
)
5DY8
(X-ray
2.03A
)
5DYB
(X-ray
2.27A
)
5DYD
(X-ray
2.48A
)
5DZ0
(X-ray
2.24A
)
5DZ1
(X-ray
2.20A
)
5DZ3
(X-ray
2.15A
)
5DZH
(X-ray
2.11A
)
5DZI
(X-ray
1.90A
)
5E0W
(X-ray
2.00A
)
5E0X
(X-ray
2.01A
)
5E14
(X-ray
2.22A
)
5E15
(X-ray
2.10A
)
5E19
(X-ray
2.24A
)
5E1C
(X-ray
1.98A
)
5EC9
(X-ray
2.30A
)
5EGV
(X-ray
2.86A
)
5EHJ
(X-ray
2.50A
)
5EI1
(X-ray
2.40A
)
5EIT
(X-ray
2.68A
)
5G3J
(X-ray
2.40A
)
5G42
(X-ray
1.72A
)
5G43
(X-ray
2.58A
)
5G44
(X-ray
1.84A
)
5G45
(X-ray
2.07A
)
5G46
(X-ray
1.76A
)
5G5W
(X-ray
2.20A
)
5H1E
(X-ray
2.60A
)
5HYR
(X-ray
2.27A
)
5I4V
(X-ray
2.61A
)
5IAW
(X-ray
2.58A
)
5ICK
(X-ray
2.47A
)
5KCC
(X-ray
2.39A
)
5KCD
(X-ray
1.82A
)
5KCE
(X-ray
1.85A
)
5KCF
(X-ray
2.07A
)
5KCT
(X-ray
1.60A
)
5KCU
(X-ray
2.03A
)
5KCW
(X-ray
1.91A
)
5KD9
(X-ray
1.78A
)
5KR9
(X-ray
2.25A
)
5KRA
(X-ray
2.40A
)
5KRC
(X-ray
2.40A
)
5KRF
(X-ray
2.19A
)
5KRH
(X-ray
2.24A
)
5KRI
(X-ray
2.25A
)
5KRJ
(X-ray
2.70A
)
5KRK
(X-ray
2.39A
)
5KRL
(X-ray
2.40A
)
5KRM
(X-ray
2.24A
)
5KRO
(X-ray
2.10A
)
5L11
(X-ray
1.85A
)
5LGA
(X-ray
2.50A
)
5LYQ
(X-ray
2.17A
)
5MK4
(X-ray
2.00A
)
5NFP
(X-ray
2.10A
)
5NFT
(X-ray
2.30A
)
5NI5
(X-ray
2.30A
)
5NI7
(X-ray
2.45A
)
5NI8
(X-ray
1.94A
)
5NIB
(X-ray
1.82A
)
5Q17
(X-ray
2.10A
)
5SYZ
(X-ray
1.93A
)
5T1Z
(X-ray
2.10A
)
5TLD
(X-ray
2.38A
)
5TLF
(X-ray
2.20A
)
5TLG
(X-ray
2.23A
)
5TLL
(X-ray
2.42A
)
5TLM
(X-ray
2.50A
)
5TLO
(X-ray
2.28A
)
5TLP
(X-ray
2.08A
)
5TLT
(X-ray
1.90A
)
5TLU
(X-ray
2.22A
)
5TLV
(X-ray
2.32A
)
5TLX
(X-ray
2.10A
)
5TLY
(X-ray
2.14A
)
5TM1
(X-ray
2.23A
)
5TM2
(X-ray
2.60A
)
5TM3
(X-ray
2.19A
)
5TM4
(X-ray
2.25A
)
5TM5
(X-ray
2.24A
)
5TM6
(X-ray
2.54A
)
5TM7
(X-ray
2.40A
)
5TM8
(X-ray
1.99A
)
5TM9
(X-ray
2.50A
)
5TML
(X-ray
2.25A
)
5TMM
(X-ray
2.20A
)
5TMO
(X-ray
2.17A
)
5TMQ
(X-ray
2.24A
)
5TMR
(X-ray
2.30A
)
5TMS
(X-ray
2.24A
)
5TMT
(X-ray
2.05A
)
5TMU
(X-ray
2.43A
)
5TMV
(X-ray
2.38A
)
5TMW
(X-ray
2.29A
)
5TMZ
(X-ray
2.21A
)
5TN1
(X-ray
2.06A
)
5TN3
(X-ray
2.54A
)
5TN4
(X-ray
1.86A
)
5TN5
(X-ray
1.89A
)
5TN6
(X-ray
2.09A
)
5TN7
(X-ray
2.24A
)
5TN8
(X-ray
2.65A
)
5U2D
(X-ray
1.86A
)
5UAN
(X-ray
3.51A
)
5VB3
(X-ray
1.95A
)
5VB5
(X-ray
2.23A
)
5VB6
(X-ray
2.04A
)
5VB7
(X-ray
2.33A
)
5VQK
(X-ray
3.10A
)
5VQL
(X-ray
2.70A
)
5WGQ
(X-ray
2.30A
)
5WZX
(X-ray
2.95A
)
5XPL
(X-ray
2.05A
)
5Y1J
(X-ray
2.00A
)
5Y49
(X-ray
2.40A
)
5YP5
(X-ray
2.65A
)
5YXB
(X-ray
2.95A
)
5YXD
(X-ray
2.98A
)
5YXJ
(X-ray
2.62A
)
5YXL
(X-ray
2.24A
)
5Z12
(X-ray
2.75A
)
6CZN
(X-ray
2.50A
)
6D0F
(X-ray
2.50A
)
6EL6
(X-ray
2.40A
)
6EL7
(X-ray
2.18A
)
6EL9
(X-ray
2.19A
)
6ESN
(X-ray
1.84A
)
6KKB
(X-ray
1.70A
)
6KKE
(X-ray
2.58A
)
6KNU
(X-ray
2.70A
)
6KNV
(X-ray
2.80A
)
6KNW
(X-ray
2.67A
)
6LB4
(X-ray
1.50A
)
6LB5
(X-ray
2.40A
)
6LB6
(X-ray
2.40A
)
6LIT
(X-ray
2.00A
)
6OQX
(X-ray
2.00A
)
6OQY
(X-ray
2.23A
)
6OR1
(X-ray
2.17A
)
6R7A
(X-ray
2.13A
)
6R7J
(X-ray
1.84A
)
6R7K
(X-ray
1.54A
)
6SJM
(X-ray
2.52A
)
6STI
(X-ray
1.89A
)
6VC2
(X-ray
1.70A
)
6VIF
(X-ray
2.26A
)
7A77
(X-ray
1.50A
)
7A78
(X-ray
1.72A
)
7A79
(X-ray
2.05A
)
7APO
(X-ray
2.40A
)
7B88
(X-ray
2.38A
)
7B9O
(X-ray
2.05A
)
7BK4
(X-ray
2.80A
)
7D42
(X-ray
2.70A
)
7JHD
(X-ray
2.40A
)
7JYD
(X-ray
2.30A
)
7JYE
(X-ray
2.55A
)
7KCO
(X-ray
1.86A
)
7NEL
(X-ray
1.45A
)
7NFB
(X-ray
1.33A
)
7NKE
(X-ray
2.35A
)
7OFI
(X-ray
1.95A
)
7OFK
(X-ray
1.61A
)
7PDQ
(X-ray
1.58A
)
7PDT
(X-ray
3.30A
)
7T2X
(X-ray
2.60A
)
7TT8
(X-ray
2.80A
)
7VUE
(X-ray
2.60A
)
7WLX
(X-ray
2.39A
)
7WMG
(X-ray
2.93A
)
7WMH
(X-ray
1.97A
)
7WMJ
(X-ray
2.81A
)
7WML
(X-ray
2.67A
)
7WMN
(X-ray
2.57A
)
7WMO
(X-ray
2.56A
)
DBSNP
rs2228591
Subcellular location [CC]
Nucleus {ECO:0000269|PubMed:8670870}.
Mouse PG classification
NA
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