| Gene Information | |
|---|---|
| Gene Name | ZIK1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 487 |
| Protein Names | Zinc finger protein interacting with ribonucleoprotein K (Zinc finger protein 762) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 93 ( ENSG00000171649 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q3SY52 |
| Gene Card | ZIK1 |
| Uniprot ID | Q3SY52 |
| Pfam | PF01352; PF00096 |
| In ASD | no |
| Allosteric Prediction | no (-1.407001631) |
| Ortholog in Animals | Alpaca_ ZIK1 ( ortholog_one2one ) Macaque_ ZIK1 ( ortholog_one2one ) Mouse_ Zik1 ( ortholog_one2one ) Rat_ Zik1 ( ortholog_one2one ) Rabbit_ ZIK1 ( ortholog_one2one ) |
| Ohnologs | ZKSCAN1 |
| Paralogs | ZNF561, ZNF562, ZNF418, IKZF5, ZNF584, ZNF304, ZNF711, PRDM15, ZFAT, ZNF419, ZNF583, ZNF8, ZNF134, ZNF154, ZNF772, ZNF256, ZBTB11, ZNF549, ZNF587B, ZNF552, ZNF837, ZNF793, ZNF660, E4F1, ZNF773, ZNF79, ZSCAN20, ZNF551, ZSCAN2, ZNF610, ZNF480, ZFY, ZFX, ZNF792, ZNF548, ZNF691, ZNF586, ZNF570 |
| Tissue | NA |
| Tissue Specificity | Expressed at high levels in gastric glands, and at low levels in colon and small intestine. Silenced through promoter methylation in gastric glands with intestinal metaplasia. {ECO:0000269|PubMed:17071588}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus {ECO:0000305}. |
| Mouse PG classification | NA |
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