| Gene Information | |
|---|---|
| Gene Name | BGR |
| Organism | Homo sapiens (Human) |
| Gene Length | 247 |
| Protein Names | C-type lectin domain family 7 member A (Beta-glucan receptor) (C-type lectin superfamily member 12) (Dendritic cell-associated C-type lectin 1) (DC-associated C-type lectin 1) (Dectin-1) (CD antigen CD369) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q9BXN2 |
| Gene Card | CLEC7A |
| Uniprot ID | Q9BXN2 |
| Pfam | PF00059 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Highly expressed in peripheral blood leukocytes and dendritic cells. Detected in spleen, bone marrow, lung, muscle, stomach and placenta. {ECO:0000269|PubMed:11470510, ECO:0000269|PubMed:11491532, ECO:0000269|PubMed:11567029, ECO:0000269|PubMed:11745369, ECO:0000269|PubMed:12423684}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs16910527 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:11745369, ECO:0000269|PubMed:16870151, ECO:0000269|PubMed:17230442}; Single-pass type II membrane protein {ECO:0000269|PubMed:11745369, ECO:0000269|PubMed:16870151, ECO:0000269|PubMed:17230442}.; [Isoform 5]: Cytoplasm {ECO:0000305}.; [Isoform 6]: Cytoplasm {ECO:0000305}.; [Isoform 7]: Cytoplasm {ECO:0000305}. |
| Mouse PG classification | NA |
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