Gene Information
Gene NameBGN
OrganismHomo sapiens (Human)
Gene Length368
Protein NamesBiglycan (Bone/cartilage proteoglycan I) (PG-S1)
Target NameNA
Target TypeNA
Gene Age454 ( ENSG00000182492 )
Evolutionary StageEuk+Bac
AlphaFoldDBP21810
Gene CardBGN
Uniprot IDP21810
PfamPF13855; PF01462
In ASDno
Allosteric Predictionno (-0.476859013)
Ortholog in AnimalsAlpaca_ BGN ( ortholog_one2one )
Dog_ BGN ( ortholog_one2one )
GuineaPig_ BGN ( ortholog_one2one )
Macaque_ BGN ( ortholog_one2one )
Mouse_ Bgn ( ortholog_one2one )
Pig_ BGN ( ortholog_one2one )
Rat_ Bgn ( ortholog_one2one )
Rabbit_ BGN ( ortholog_one2one )
OhnologsNA
ParalogsLRTM1, LRRTM3, LRRTM1, LRRC19, RTN4RL2, LRRC4B, NYX, PODN, LRRC15, FLRT2, FLRT1, LRRTM4, LRRC66, RTN4RL1, LRRC4, ASPN, PODNL1, FLRT3, DCN, GP1BA, RTN4R, LRRC4C
TissueNA
Tissue SpecificityFound in several connective tissues, especially in articular cartilages.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs886037825  rs879255604  rs879255605  rs886037824 
Subcellular location [CC]Secreted, extracellular space, extracellular matrix {ECO:0000250}.
Mouse PG classificationHPG
click here to return to the previous page