| Gene Information | |
|---|---|
| Gene Name | BFAR |
| Organism | Homo sapiens (Human) |
| Gene Length | 450 |
| Protein Names | Bifunctional apoptosis regulator (RING finger protein 47) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000103429 ) 3 ( ENSG00000275618 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q9NZS9 |
| Gene Card | BFAR |
| Uniprot ID | Q9NZS9 |
| Pfam | PF00536 |
| In ASD | no |
| Allosteric Prediction | no (-1.411603552) |
| Ortholog in Animals | Alpaca_ BFAR ( ortholog_one2one ) Dog_ BFAR ( ortholog_one2one ) GuineaPig_ BFAR ( ortholog_one2one ) Macaque_ BFAR ( ortholog_one2one ) Mouse_ Bfar ( ortholog_one2one ) Pig_ BFAR ( ortholog_one2one ) Rat_ Bfar ( ortholog_one2one ) Rabbit_ BFAR ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed highly in brain, moderately in small intestine, weakly in testes and only faintly in liver and skeletal muscle. Not expressed in heart, kidney, lung and spleen. {ECO:0000269|PubMed:10716992, ECO:0000269|PubMed:14502241}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs11546303 rs35377618 |
| Subcellular location [CC] | Endoplasmic reticulum membrane {ECO:0000269|PubMed:10716992, ECO:0000269|PubMed:14502241}; Multi-pass membrane protein {ECO:0000269|PubMed:10716992, ECO:0000269|PubMed:14502241}. |
| Mouse PG classification | NA |
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