| Gene Information | |
|---|---|
| Gene Name | BF |
| Organism | Homo sapiens (Human) |
| Gene Length | 764 |
| Protein Names | Complement factor B (EC 3.4.21.47) (C3/C5 convertase) (Glycine-rich beta glycoprotein) (GBG) (PBF2) (Properdin factor B) [Cleaved into: Complement factor B Ba fragment; Complement factor B Bb fragment] |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | P00751 |
| Gene Card | CFB |
| Uniprot ID | P00751 |
| Pfam | PF00084; PF00089; PF00092 |
| In ASD | yes |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.02(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
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| PDB | 1DLE (X-ray 2.10A ) 1Q0P (X-ray 1.80A ) 1RRK (X-ray 2.00A ) 1RS0 (X-ray 2.60A ) 1RTK (X-ray 2.30A ) 2OK5 (X-ray 2.30A ) 2WIN (X-ray 3.90A ) 2XWB (X-ray 3.49A ) 2XWJ (X-ray 4.00A ) 3HRZ (X-ray 2.20A ) 3HS0 (X-ray 3.00A ) 6QSW (X-ray 1.64A ) 6QSX (X-ray 1.77A ) 6RAV (X-ray 1.70A ) 6RUR (X-ray 6.00A ) 6RUV (X-ray 6.15A ) 6T8U (X-ray 2.84A ) 6T8V (X-ray 2.29A ) 6T8W (X-ray 1.70A ) 7JTN (X-ray 3.10A ) 7JTQ (X-ray 3.50A ) 7NOZ (X-ray 3.90A ) |
| DBSNP | rs4151667 rs641153 rs12614 rs745794224 rs144812066 rs4151651 rs117905900 rs121909748 rs200837114 rs149101394 rs4151659 rs4151660 |
| Subcellular location [CC] | Secreted. |
| Mouse PG classification | NA |
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