| Gene Information | |
|---|---|
| Gene Name | TMBIM4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 238 |
| Protein Names | Protein lifeguard 4 (Golgi anti-apoptotic protein) (Protein S1R) (Transmembrane BAX inhibitor motif-containing protein 4) (Z-protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000155957 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9HC24 |
| Gene Card | TMBIM4 |
| Uniprot ID | Q9HC24 |
| Pfam | PF01027 |
| In ASD | no |
| Allosteric Prediction | no (-0.673939974) |
| Ortholog in Animals | Alpaca_ TMBIM4 ( ortholog_one2one ) Dog_ TMBIM4 ( ortholog_one2one ) GuineaPig_ TMBIM4 ( ortholog_one2one ) Macaque_ TMBIM4 ( ortholog_one2one ) Mouse_ Tmbim4 ( ortholog_one2one ) Pig_ TMBIM4 ( ortholog_one2one ) Rat_ Tmbim4 ( ortholog_one2one ) Rabbit_ TMBIM4 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | TMBIM1, GRINA, FAIM2, GHITM, TMBIM6 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs11176070 rs8793 |
| Subcellular location [CC] | Golgi apparatus membrane {ECO:0000269|PubMed:17319741, ECO:0000269|PubMed:22418439}; Multi-pass membrane protein {ECO:0000269|PubMed:17319741, ECO:0000269|PubMed:22418439}. |
| Mouse PG classification | NA |
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