| Gene Information | |
|---|---|
| Gene Name | IL22 |
| Organism | Homo sapiens (Human) |
| Gene Length | 179 |
| Protein Names | Interleukin-22 (IL-22) (Cytokine Zcyto18) (IL-10-related T-cell-derived-inducible factor) (IL-TIF) |
| Target Name | interleukin-22 |
| Target Type | Clinical trial target |
| Gene Age | 132 ( ENSG00000127318 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q9GZX6 |
| Gene Card | IL22 |
| Uniprot ID | Q9GZX6 |
| Pfam | PF14565 |
| In ASD | no |
| Allosteric Prediction | no (-0.229283617) |
| Ortholog in Animals | Alpaca_ IL22 ( ortholog_one2one ) Dog_ IL22 ( ortholog_one2one ) GuineaPig_ IL22 ( ortholog_one2one ) Macaque_ IL22 ( ortholog_one2one ) Mouse_ Il22 ( ortholog_one2many ) Mouse_ Il22b ( ortholog_one2many ) Pig_ IL22 ( ortholog_one2one ) Rat_ Il22 ( ortholog_one2one ) Rabbit_ IL22 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.003490(Rat);0.133333(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1M4R (X-ray 2.00A ) 1YKB (X-ray 2.60A ) 3DGC (X-ray 2.50A ) 3DLQ (X-ray 1.90A ) 3G9V (X-ray 2.76A ) 3Q1S (X-ray 2.15A ) |
| DBSNP | rs2227507 |
| Subcellular location [CC] | Secreted. |
| Mouse PG classification | NA |
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