| Gene Information | |
|---|---|
| Gene Name | BDTK |
| Organism | Homo sapiens (Human) |
| Gene Length | 1321 |
| Protein Names | Tau-tubulin kinase 1 (EC 2.7.11.1) (Brain-derived tau kinase) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q5TCY1 |
| Gene Card | TTBK1 |
| Uniprot ID | Q5TCY1 |
| Pfam | PF00069 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in the brain, particularly in cortical and hippocampal neurons. Weakly expressed in spinal cord and testis. No expression in adipose tissue, bladder, cervix, colon, esophagus, heart, kidney, liver, lung, ovary, placenta, prostate, skeletal muscle, small intestine, spleen, testis, thymus, thyroid or trachea. {ECO:0000269|PubMed:16923168}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4BTJ (X-ray 2.16A ) 4BTK (X-ray 2.00A ) 4BTM (X-ray 2.54A ) 4NFM (X-ray 2.12A ) 4NFN (X-ray 1.42A ) 7JXX (X-ray 1.56A ) 7JXY (X-ray 2.15A ) 7Q8V (X-ray 2.13A ) 7Q8W (X-ray 2.02A ) |
| DBSNP | rs34993661 rs3800294 rs35175743 rs56377340 rs3800295 rs267601046 rs3800297 rs3800298 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:16923168}. |
| Mouse PG classification | NA |
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