| Gene Information | |
|---|---|
| Gene Name | RHPN2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 686 |
| Protein Names | Rhophilin-2 (76 kDa RhoB effector protein) (GTP-Rho-binding protein 2) (p76RBE) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000131941 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q8IUC4 |
| Gene Card | RHPN2 |
| Uniprot ID | Q8IUC4 |
| Pfam | PF03097; PF02185 |
| In ASD | no |
| Allosteric Prediction | no (-0.438300779) |
| Ortholog in Animals | Alpaca_ RHPN2 ( ortholog_one2one ) Dog_ RHPN2 ( ortholog_one2one ) GuineaPig_ RHPN2 ( ortholog_one2one ) Macaque_ RHPN2 ( ortholog_one2one ) Mouse_ Rhpn2 ( ortholog_one2one ) Pig_ RHPN2 ( ortholog_one2one ) Rat_ Rhpn2 ( ortholog_one2one ) Rabbit_ RHPN2 ( ortholog_one2one ) |
| Ohnologs | RHPN1 |
| Paralogs | RHPN1 |
| Tissue | brain |
| Tissue Specificity | Widely expressed. Highly expressed in prostate, trachea, stomach, colon, thyroid and pancreas. Expressed at lower level in brain, spinal cord, kidney, placenta and liver. {ECO:0000269|PubMed:12221077, ECO:0000269|PubMed:12473120}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | 2VSV (X-ray 1.82A ) |
| DBSNP | rs28626308 rs28407794 |
| Subcellular location [CC] | Cytoplasm, perinuclear region {ECO:0000269|PubMed:12473120}. |
| Mouse PG classification | NA |
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