| Gene Information | |
|---|---|
| Gene Name | BCR |
| Organism | Homo sapiens (Human) |
| Gene Length | 1271 |
| Protein Names | Breakpoint cluster region protein (EC 2.7.11.1) (Renal carcinoma antigen NY-REN-26) |
| Target Name | breakpoint cluster region protein |
| Target Type | NA |
| Gene Age | 382 ( ENSG00000186716 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P11274 |
| Gene Card | BCR |
| Uniprot ID | P11274 |
| Pfam | PF09036; PF00168; PF00620; PF00621 |
| In ASD | no |
| Allosteric Prediction | yes (0.745123132) |
| Ortholog in Animals | Alpaca_ BCR ( ortholog_one2one ) GuineaPig_ BCR ( ortholog_one2one ) Macaque_ BCR ( ortholog_one2one ) Mouse_ Bcr ( ortholog_one2one ) Pig_ BCR ( ortholog_one2one ) Rat_ Bcr ( ortholog_one2one ) Rabbit_ BCR ( ortholog_one2one ) |
| Ohnologs | ABR |
| Paralogs | ABR |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | 0.000730(Chimpanzee);0.001000(Mouse);0.001942(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1K1F (X-ray 2.20A ) 2AIN (NMR - ) 5N6R (NMR - ) 5N7E (X-ray 1.65A ) 5OC7 (X-ray 1.65A ) |
| DBSNP | rs56321828 rs4437065 rs12484731 rs140504 rs35537221 rs2229038 rs776552570 rs778229520 rs745459086 rs11558696 rs879255379 rs35812689 rs200099830 rs1195127922 rs55816482 rs56265970 rs55719322 |
| Subcellular location [CC] | Postsynaptic density {ECO:0000250|UniProtKB:Q6PAJ1}. Cell projection, dendritic spine {ECO:0000250|UniProtKB:Q6PAJ1}. Cell projection, axon {ECO:0000250|UniProtKB:Q6PAJ1}. Synapse {ECO:0000250|UniProtKB:F1LXF1}. |
| Mouse PG classification | NA |
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