| Gene Information | |
|---|---|
| Gene Name | BCNG2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 889 |
| Protein Names | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q9UL51 |
| Gene Card | HCN2 |
| Uniprot ID | Q9UL51 |
| Pfam | PF00027; PF00520; PF08412 |
| In ASD | yes |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Highly expressed throughout the brain. Detected at low levels in heart. {ECO:0000269|PubMed:10228147, ECO:0000269|PubMed:9630217}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2MPF (NMR - ) 3U10 (X-ray 2.30A ) |
| DBSNP | rs114790896 rs55687900 rs200188844 rs1230549709 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:10228147, ECO:0000269|PubMed:10524219}; Multi-pass membrane protein {ECO:0000269|PubMed:10228147, ECO:0000269|PubMed:10524219}. |
| Mouse PG classification | NA |
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