| Gene Information | |
|---|---|
| Gene Name | MOGAT3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 341 |
| Protein Names | 2-acylglycerol O-acyltransferase 3 (EC 2.3.1.20) (EC 2.3.1.22) (Acyl-CoA:monoacylglycerol acyltransferase 3) (MGAT3) (Diacylglycerol O-acyltransferase candidate 7) (hDC7) (Diacylglycerol acyltransferase 2-like protein 7) (Monoacylglycerol O-acyltransferase 3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 382 ( ENSG00000106384 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q86VF5 |
| Gene Card | MOGAT3 |
| Uniprot ID | Q86VF5 |
| Pfam | PF03982 |
| In ASD | no |
| Allosteric Prediction | no (-0.900349233) |
| Ortholog in Animals | Alpaca_ MOGAT3 ( ortholog_one2many ) Dog_ MOGAT3 ( ortholog_one2one ) Macaque_ MOGAT3 ( ortholog_one2one ) |
| Ohnologs | DGAT2L6, MOGAT1 |
| Paralogs | AWAT2, AWAT1, DGAT2L6, DGAT2, MOGAT2, MOGAT1 |
| Tissue | colon, duodenum, small.intestine, rectum, small.intestine.Peyers.patch, transverse.colon |
| Tissue Specificity | Selectively expressed in the digestive system. Highly expressed in the ileum, and at lower level in jejunum, duodenum, colon, cecum and the rectum. Not expressed in the stomach and the esophagus and trachea. Expressed at very low level in liver. {ECO:0000269|PubMed:12618427}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Endoplasmic reticulum membrane {ECO:0000269|PubMed:27184406}; Multi-pass membrane protein {ECO:0000305}. Cytoplasm, perinuclear region {ECO:0000269|PubMed:27184406}. |
| Mouse PG classification | NA |
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