| Gene Information | |
|---|---|
| Gene Name | PLXNA1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1896 |
| Protein Names | Plexin-A1 (Semaphorin receptor NOV) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000114554 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q9UIW2 |
| Gene Card | PLXNA1 |
| Uniprot ID | Q9UIW2 |
| Pfam | PF08337; PF20170; PF01437; PF01403; PF01833; PF18020; PF17960 |
| In ASD | no |
| Allosteric Prediction | no (-0.215100251) |
| Ortholog in Animals | Alpaca_ PLXNA1 ( ortholog_one2one ) Dog_ PLXNA1 ( ortholog_one2one ) GuineaPig_ PLXNA1 ( ortholog_one2one ) Macaque_ PLXNA1 ( ortholog_one2one ) Mouse_ Plxna1 ( ortholog_one2one ) Pig_ PLXNA1 ( ortholog_one2one ) Rat_ Plxna1 ( ortholog_one2one ) Rabbit_ PLXNA1 ( ortholog_one2one ) |
| Ohnologs | PLXNA3, PLXNB1, PLXNB3, PLXNA4, PLXNA2 |
| Paralogs | PLXNA3, PLXNA2, PLXNA4, PLXNB2, PLXND1, PLXNC1, PLXNB3, PLXNB1 |
| Tissue | NA |
| Tissue Specificity | Detected in fetal brain, lung, liver and kidney. {ECO:0000269|PubMed:8570614}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.066667(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000250}. |
| Mouse PG classification | NA |
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