| Gene Information | |
|---|---|
| Gene Name | BCH |
| Organism | Homo sapiens (Human) |
| Gene Length | 468 |
| Protein Names | Beta-chimaerin (Beta-chimerin) (Rho GTPase-activating protein 3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | P52757 |
| Gene Card | CHN2 |
| Uniprot ID | P52757 |
| Pfam | PF00130; PF00620; PF00017 |
| In ASD | yes |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Highest levels in the brain and pancreas. Also expressed in the heart, placenta, and weakly in the kidney and liver. Expression is much reduced in the malignant gliomas, compared to normal brain or low-grade astrocytomas. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1XA6 (X-ray 3.20A ) |
| DBSNP | rs3750103 rs34971642 |
| Subcellular location [CC] | Membrane {ECO:0000305}; Peripheral membrane protein {ECO:0000305}. |
| Mouse PG classification | NA |
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