| Gene Information | |
|---|---|
| Gene Name | BCAS2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 225 |
| Protein Names | Pre-mRNA-splicing factor SPF27 (Breast carcinoma-amplified sequence 2) (DNA amplified in mammary carcinoma 1 protein) (Spliceosome-associated protein SPF 27) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000116752 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | O75934 |
| Gene Card | BCAS2 |
| Uniprot ID | O75934 |
| Pfam | PF05700 |
| In ASD | no |
| Allosteric Prediction | no (-1.10011431) |
| Ortholog in Animals | Alpaca_ BCAS2 ( ortholog_one2one ) Dog_ BCAS2 ( ortholog_one2one ) GuineaPig_ BCAS2 ( ortholog_one2one ) Macaque_ BCAS2 ( ortholog_one2one ) Mouse_ Bcas2 ( ortholog_one2one ) Pig_ BCAS2 ( ortholog_one2one ) Rat_ Bcas2 ( ortholog_one2one ) Rabbit_ BCAS2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Ubiquitously expressed. {ECO:0000269|PubMed:10403562}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.028194(Rat);0.156624(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5MQF (EM 5.90A ) 5XJC (EM 3.60A ) 5YZG (EM 4.10A ) 5Z56 (EM 5.10A ) 5Z57 (EM 6.50A ) 6FF7 (EM 4.50A ) 6ICZ (EM 3.00A ) 6ID0 (EM 2.90A ) 6ID1 (EM 2.86A ) 6QDV (EM 3.30A ) 7A5P (EM 5.00A ) 7W59 (EM 3.60A ) 7W5A (EM 3.60A ) 7W5B (EM 4.30A ) |
| DBSNP | rs1197668726 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:12169396, ECO:0000269|PubMed:20176811, ECO:0000269|PubMed:28076346, ECO:0000269|PubMed:28502770, ECO:0000269|PubMed:29301961, ECO:0000269|PubMed:29360106, ECO:0000269|PubMed:30705154}. Nucleus, nucleolus {ECO:0000269|PubMed:12429849}. |
| Mouse PG classification | NA |
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