| Gene Information | |
|---|---|
| Gene Name | POLD2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 469 |
| Protein Names | DNA polymerase delta subunit 2 (DNA polymerase delta subunit p50) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000106628 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P49005 |
| Gene Card | POLD2 |
| Uniprot ID | P49005 |
| Pfam | PF18018; PF04042 |
| In ASD | no |
| Allosteric Prediction | no (-0.049953609) |
| Ortholog in Animals | Alpaca_ POLD2 ( ortholog_one2many ) Dog_ POLD2 ( ortholog_one2one ) GuineaPig_ POLD2 ( ortholog_one2one ) Macaque_ POLD2 ( ortholog_one2one ) Mouse_ Pold2 ( ortholog_one2one ) Pig_ POLD2 ( ortholog_one2one ) Rat_ Pold2 ( ortholog_one2one ) Rabbit_ POLD2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.120833(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3E0J (X-ray 3.00A ) 6S1M (EM 4.27A ) 6S1N (EM 4.86A ) 6S1O (EM 8.10A ) 6TNY (EM 3.08A ) 6TNZ (EM 4.05A ) |
| DBSNP | rs3087366 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:22801543}. Note=Recruited to DNA damage sites within 2 hours following UV irradiation. {ECO:0000269|PubMed:22801543}. |
| Mouse PG classification | NA |
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