| Gene Information | |
|---|---|
| Gene Name | BAZ2A |
| Organism | Homo sapiens (Human) |
| Gene Length | 1905 |
| Protein Names | Bromodomain adjacent to zinc finger domain protein 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3) |
| Target Name | bromodomain adjacent to zinc finger 2a |
| Target Type | Literature-reported target |
| Gene Age | >4290 ( ENSG00000076108 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q9UIF9 |
| Gene Card | BAZ2A |
| Uniprot ID | Q9UIF9 |
| Pfam | PF00439; PF02791; PF01429; PF00628; PF15612; PF15613 |
| In ASD | no |
| Allosteric Prediction | no (-0.295902223) |
| Ortholog in Animals | Alpaca_ BAZ2A ( ortholog_one2one ) GuineaPig_ BAZ2A ( ortholog_one2one ) Macaque_ BAZ2A ( ortholog_one2one ) Mouse_ Baz2a ( ortholog_one2one ) Pig_ BAZ2A ( ortholog_one2one ) Rat_ Baz2a ( ortholog_one2one ) Rabbit_ BAZ2A ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | BAZ1A, BRD4, BRDT, KAT2A, CECR2, BAZ1B, BRD3, BRD2, BAZ2B, KAT2B, BPTF |
| Tissue | NA |
| Tissue Specificity | Expressed at moderate levels in most tissues analyzed, including heart, brain, placenta, lung, skeletal muscle, kidney and pancreas. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.044444(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | 4LZ2 (X-ray 1.76A ) 4Q6F (X-ray 1.91A ) 4QBM (X-ray 1.65A ) 4QF2 (X-ray 1.70A ) 5AGQ (NMR - ) 5MGJ (X-ray 2.10A ) 5MGK (X-ray 2.30A ) 5MGL (X-ray 2.65A ) 5MGM (X-ray 2.80A ) 5OR8 (X-ray 2.40A ) 5T8R (X-ray 2.40A ) 6FAP (X-ray 2.70A ) 6FG6 (X-ray 2.40A ) 6FGF (X-ray 2.80A ) 6FGG (X-ray 1.10A ) 6FGH (X-ray 2.10A ) 6FGI (X-ray 2.55A ) 6FGL (X-ray 2.10A ) 6FGV (X-ray 2.50A ) 6FGW (X-ray 2.73A ) 6FHU (X-ray 2.00A ) 6FI0 (X-ray 1.90A ) 6FKP (X-ray 2.00A ) 7B7B (X-ray 1.40A ) 7B7G (X-ray 1.43A ) 7B7I (X-ray 1.15A ) 7B82 (X-ray 1.25A ) 7BC2 (X-ray 2.00A ) 7BL8 (X-ray 2.50A ) 7BL9 (X-ray 1.30A ) 7BLA (X-ray 1.09A ) 7BLB (X-ray 2.30A ) 7BLC (X-ray 2.30A ) 7BLD (X-ray 2.35A ) 7FHJ (X-ray 2.28A ) 7MWH (X-ray 2.28A ) 7MWI (X-ray 1.80A ) 7MWL (X-ray 1.84A ) |
| DBSNP | rs2230579 |
| Subcellular location [CC] | Nucleus, nucleolus {ECO:0000250|UniProtKB:Q91YE5}. Note=Colocalizes with the basal RNA polymerase I transcription factor UBF in the nucleolus. {ECO:0000250|UniProtKB:Q91YE5}. |
| Mouse PG classification | NA |
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